网站首页期刊介绍通知公告编 委 会投稿须知电子期刊广告合作联系我们
最新消息:
老年患者行腹腔镜下胆总管探查一期缝合的可行性研究
作者:陆淼  闫凯  胡方方  潘峥 
单位:东南大学附属中大医院 肝胆胰中心, 江苏 南京 210009
关键词:腹腔镜下胆总管探查术 一期缝合 老年患者 
分类号:R657.4
出版年·卷·期(页码):2025·53·第七期(1110-1114)
摘要:

目的:观察腹腔镜下胆总管探查术(LCBDE)一期缝合治疗老年患者胆总管结石的疗效及可行性。方法:回顾分析东南大学附属中大医院肝胆胰中心单一医疗组2018年9月至2024年8月接受腹腔镜下胆总管探查一期缝合术的130例患者的临床资料,130例患者分为47例≥65岁的老年患者组和83例<65岁的非老年患者组,通过比较两组患者一般资料、手术及术后情况(手术时间、术后住院天数、术后并发症发生率、结石再发率),分析老年患者行LCBDE一期缝合的安全性和可行性。结果:老年患者组与非老年患者组相比,合并症数量、ASA分级、上腹部手术史、白蛋白、总胆红素、胆总管直径均有明显的差异。两组患者手术时间、术中出血量、术后住院天数、术后并发症率、围手术期再手术率、术后结石再发率均无明显差异。但老年患者组有4人术后需要转ICU监护,与非老年患者组相比有明显差异(P=0.03)。结论:在严格掌握手术适应症的情况下对老年患者行LCBDE一期缝合是安全可行的。

Objective: To observe the efficacy and feasibility of primary closure following laparoscopic common bile duct exploration(LCBDE)for elderly patients with common bile duct stones.Methods: A retrospective analysis was conducted on the clinical data of 130 patients who underwent primary closure following LCBDE from September 2018 to August 2024 in Hepatobiliary and Pancreatic Center, Zhongda Hospital Affiliated to Southeast University. The patients were divided into two groups: 47 elderly patients aged 65 and above and 83 patients under 65. General data as well as surgical and postoperative outcomes were compared to analyze the safety and feasibility of LCBDE primary suture in elderly patients. Results: There were no significant differences between the two groups in terms of gender, WBC, and neutrophil ratio. Compared to the non-elderly group, the elderly group showed significant differences in the number of comorbidities, ASA classification, history of upper abdominal surgery, albumin level, total bilirubin level, and common bile duct diameter. There were no significant differences in operation time, intraoperative blood loss, postoperative hospital stay, postoperative complication rate, perioperative reoperation rate, and postoperative stone recurrence rate between the two groups. However, 4 patients in Group A required ICU monitoring postoperatively, showing a significant difference compared to Group B(P=0.03).Conclusion: Performing primary closure following LCBDE in elderly patients is safe and feasible when surgical indications are strictly controlled.

参考文献:

[1] LI S,GUIZZETTI L,MA C,et al.Epidemiology and outcomes of choledocholithiasis and cholangitis in the United States:trends and urban-rural variations[J].BMC Gastroenterol,2023,23(1):254.
[2] 张君来.基于系统动力学的中国人口老龄化解析及其对卫生总费用的影响和预测[D].南昌:江西财经大学,2024.
[3] FIGUEIREDO J C,HAIMAN C,PORCEL J,et al.Sex and ethnic/racial-specific risk factors for gallbladder disease[J].BMC Gastroenterol,2017,17(1):153.
[4] BUXBAUM J L,ABBAS FEHMI S M,SULTAN S,et al.ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis[J].Gastrointest Endosc,2019,89(6):1075-1105.e15.
[5] LAN W F,LI J H,WANG Q B,et al.Comparison of laparoscopic common bile duct exploration and endoscopic retrograde cholangiopancreatography combined with laparoscopic cholecystectomy for patients with gallbladder and common bile duct stones a Meta-analysis of randomized controlled trials[J].Eur Rev Med Pharmacol Sci,2023,27(10):4656-4669.
[6] RICCI C,PAGANO N,TAFFURELLI G,et al.Comparison of efficacy and safety of 4 combinations of laparoscopic and intraoperative techniques for management of gallstone disease with biliary duct calculi:a systematic review and network Meta-analysis[J].JAMA Surg,2018,153(7):e181167.
[7] ZHOU Y,ZHA W Z,FAN R G,et al.Two-stage versus single-stage procedure for the management of cholecystocholedocholithiasis in elderly patients:a retrospectively cohort study[J].Rev Esp Enferm Dig,2019,111(3):176-181.
[8] KIM H,SHIN S P,HWANG J W,et al.Outcomes of laparoscopic common bile duct exploration(LCBDE) after failed endoscopic retrograde cholangiopancreatography versus primary LCBDE for managing cholecystocholedocholithiasis[J].J Int Med Res,2020,48(10):300060520957560.
[9] Di MAURO D,RICCIARDI E,SIRAGUSA L,et al.Outcome of laparoscopic common bile duct exploration after failed endoscopic retrograde cholangiopancreatography:a comparative study[J].J Laparoendosc Adv Surg Tech A,2019,29(11):1391-1396.
[10] LIAO Y,LIU F,ZHANG X,et al.The safety and efficacy of primary duct closure after laparoscopic common bile duct exploration in patients with mild-to-moderate calculus-associated acute cholangitis:a retrospective cohort study[J].Updates Surg,2024,76(8):2767-2775.
[11] TENG D,XU Y,YANG Q,et al.The efficacy and safety of laparoscopic common bile duct exploration with primary duct closure for cholecystolithiasis combined with choledocholithiasis[J].Clin Case Rep,2024,12(9):e9414.
[12] 王翔,牛帅,尹燕楠,等.内镜逆行胰胆管造影治疗先天性胆总管囊肿切除术后胆总管残端结石[J].肝胆胰外科杂志,2024,36(8):476-480.
[13] 朱鸣雷,刘晓红.老年患者围术期风险评估及管理[J].中华老年医学杂志,2020,39(7):741-743.
[14] 郭晓波,韩伟,姜晶梅,等.普外科不同年龄老年住院手术患者手术安全性比较[J].中国医学科学院学报,2023,45(4):549-555.
[15] ZHANG D,MA F,SUN W et al.Primary suture for patients of bile duct stones after laparoscopic biliary tract exploration:a retrospective cohort study[J].Updates Surg,2023,75(4):897-903.
[16] SHENG H,DOU M,WANG J et al.Comparative efficacy of laparoscopic choledocholithotomy with T-tube insertion vs.primary suture in the management of cholecystolithiasis complicated by choledocholithiasis[J].Am J Transl Res,2024,16(7):3139-3147.
[17] LIU D,CAO F,LIU J et al.Risk factors for bile leakage after primary closure following laparoscopic common bile duct exploration:a retrospective cohort study[J].BMC Surg,2017,17(1):1.
[18] DE SILVA H M, HOWARD T, BIRD D, et al. Outcomes following common bile duct exploration versus endoscopic stone extraction before, during and after laparoscopic cholecystectomy for patients with common bile duct stones[J]. HPB(Oxford),2022,24(12):2125-2133.
[19] WU P H, YU M W, CHUANG S C, et al. Comparison of laparoscopic common bile duct exploration plus cholecystectomy and endoscopic retrograde cholangiopancreatography followed by laparoscopic cholecystectomy for elderly patients with common bile duct stones and gallbladder stones[J]. J Gastrointest Surg,2024,28(5):719-724.

服务与反馈:
文章下载】【发表评论】【查看评论】【加入收藏
提示:您还未登录,请登录!点此登录
您是第 971370 位访问者


 ©《现代医学》编辑部
联系电话:025-83272481;83272479
电子邮件: xdyx@pub.seu.edu.cn

本系统由北京博渊星辰网络科技有限公司设计开发 技术支持电话:010-63361626

苏ICP备09058541