精神分裂症患者敌意归因偏向与PANSS评分、睡眠质量的相关性研究-现代医学

精神分裂症患者敌意归因偏向与PANSS评分、睡眠质量的相关性研究

单位：安徽省宿州市第二人民医院精神科, 安徽宿州 234000

分类号：R749.3

出版年·卷·期（页码）：2025·53·第一期（68-74）

摘要：

目的: 探究精神分裂症患者敌意归因偏向与阳性和阴性症状量表(PANSS)评分、睡眠质量相关性。方法: 选择2022年1月至2024年3月我院收治的110例精神分裂症患者为研究组，同时选择同期在我院体检的健康者42例为对照组，采用中文版模棱两可、目的和敌意问卷(AIHQ-C)、PANSS评分、匹兹堡睡眠质量指数(PSQI)分别评估并比较两组敌意归因偏向、神经症状及睡眠质量，分析AIHQ-C评分与PANSS评分、PSQI的相关性；收集研究组患者相关资料，分析患者敌意归因偏向影响因素。结果: 研究组患者责备偏向、敌意偏向、攻击偏向评分与AIHQ-C总评分均高于对照组，一般精神病理症状、阳性症状、阴性症状评分与PANSS评分高于对照组，催眠药物、睡眠质量、睡眠效率、入睡时间、睡眠障碍、睡眠时间、日间功能障碍与PSQI评分高于对照组(P＜0.05)；Pearson相关性分析AIHQ-C评分与PANSS评分及PSQI评分呈正相关(P＜0.05)；单因素与多元线性回归分析显示，年龄、学历、病程为患者敌意归因偏向影响因素(P＜0.05)，是否合并基础疾病、家庭收入、发病情况为非患者敌意归因偏向影响因素(P＞0.05)。结论: 精神分裂症患者存在显著敌意归因偏向趋势，其与患者PANSS评分、睡眠质量关系密切，且会受年龄、学历、病程等因素影响。

Objective: To explore the correlation between the hostility attribution bias and the Positive and Negative Symptom Scale(PANSS) scores and sleep quality in patients with schizophrenia. Methods: A total of 110 patients with schizophrenia admitted to our hospital from January 2022 to March 2024 were selected as study group. At the same time, 42 healthy subjects were selected as control group. The Chinese version of ambiguous, intentions and hostility questionnaire(AIHQ-C), PANSS score and Pittsburgh sleep quality index(PSQI) were used to evaluate and compare the hostility attribution bias, neurological symptoms and sleep quality of the two groups, respectively. The correlation among AIHQ-C score, PANSS score and PSQI was analyzed. The related data of patients in the study group were collected and the influencing factors of patients' hostility attribution bias were analyzed. Results: The scores of blame bias, hostility bias, aggression bias and AIHQ-C in the study group were higher than those in the control group. The scores of general psychopathological symptoms, positive symptoms, negative symptoms and PANSS were higher, and hypnotic drugs, sleep quality, sleep efficiency, sleep time, sleep disorder, sleep time, daytime dysfunction and PSQI scores were higher than those in the the study group(P<0.05). Pearson correlation analysis showed that AIHQ-C score was positively correlated with PANSS score and PSQI score(P<0.05). Univariate and multiple linear regression analyses showed that age, educational background and course of disease were the influencing factors of hostility attribution bias(P<0.05). The combination of underlying disease, family income, and morbidity were not the influencing factors(P>0.05). Conclusion: There is a significant trend of hostility attribution bias in patients with schizophrenia, which is closely related to PANSS score and sleep quality of patients, and is affected by age, education, course of disease and other factors.

参考文献：

[1] DRIVER D I,THOMAS S,GOGTAY N,et al.Childhood-onset schizophrenia and early-onset schizophrenia spectrum disorders:an update[J].Child Adolesc Psychiatr Clin N Am,2020,29(1):71-90.
[2] 朱文凤，夏凌翔.大学生神经质纵向预测攻击行为的时间路径模型:敌意归因偏向和愤怒沉浸的双向中介作用[J].心理与行为研究，2021，19(3):396-402.
[3] 权方英，夏凌翔.敌意归因偏向对反应性攻击的预测及报复动机的中介作用[J].心理科学，2019，42(6):1434-1440.
[4] BUCK B,BROWNE J,GAGEN E C,et al.Hostile attribution bias in schizophrenia-spectrum disorders:narrative review of the literature and persisting questions[J].J Ment Health,2023,32(1):132-149.
[5] HIERONYMUS F,CORRELL C U,ØSTERGAARD S D.Initial severity of the Positive and Negative Syndrome Scale(PANSS)-30,its main subscales plus the PANSS-6,and the relationship to subsequent improvement and trial dropout:a pooled participant-level analysis of 18 placebo-controlled risperidone and paliperidone trials[J].Transl Psychiatry,2023,13(1):191-203.
[6] 杨静静，谭文艳，王诗镔，等.广东省精神分裂症患者生活质量及影响因素分析[J].重庆医学，2021，50(7):1199-1204.
[7] 范肖冬.ICD-10 精神与行为障碍分类[M].北京:人民卫生出版社，1993：72-78.
[8] 陈学全，董毅，DENNIS R，等.中文版模棱两可、目的和敌意问卷的信效度[J].中华行为医学与脑科学杂志，2012，21(11):1038-1041.
[9] KAY S R,FISZBEIN A,OPLER L A.The Positive and Negative Syndrome Scale(PANSS) for schizophrenia[J].Schizophr Bull,1987,13(2):261-276.
[10] Buysse D J,Reynolds C F,Monk T H,et al.The pittsburgh sleep quality index:a new instrument for psychiatric practice and research[J].Psychiatry Res,1989,28(2):193-213.
[11] 李娟.奥氮平联合不同剂量二甲双胍治疗精神分裂症临床对比研究[J].东南大学学报(医学版)，2021，40(4):524-527.
[12] SUBRA B.Why narcissists are more likely to be aggressive? The role of hostile attribution bias[J].Int J Psychol,2023,58(6):518-525.
[13] VANWALLEGHEM S,MILJKOVITCH R,VINTER A.Effects of intellectual disability and attachment on hostile intent attribution bias[J].Attach Hum Dev,2022,24(6):732-749.
[14] 陈莉，李光芸，聂芸，等.精神分裂症患者童年创伤与认知功能损害、敌意归因偏向和自我怜悯能力的相关性研究[J].现代生物医学进展，2022，22(15):2932-2936.
[15] NEUMANN D,SANDER A M,PERKINS S M,et al.Negative attribution bias and related risk factors after brain injury[J].J Head Trauma Rehabil,2021,36(1):61-70.
[16] LIN S,WANG Y,CHENG G,et al.Relationship between harsh parenting and aggressive behaviors in male juvenile delinquents:potential mediating roles of peer victimization and hostile attribution bias[J].Behav Sci(Basel),2023,13(7):610-618.
[17] 李慧，张许来，张爱国.精神分裂症患者梦威胁模拟水平与敌意归因偏向及精神症状的关系[J].安徽医学，2022，43(10):1121-1125.
[18] 陈学全，高莉玲，万兴松，等.精神分裂症病人敌意归因偏向及其影响因素分析[J].安徽医药，2021，25(8):1514-1517.
[19] CHEN M H,KORENIC S A,WICKWIRE E M,et al.Sex differences in subjective sleep quality patterns in schizophrenia[J].Behav Sleep Med,2020,18(5):668-679.
[20] YE Z,WU D,YUE Y,et al.The relationship between sleep disturbance and aggressive behaviour among community-dwelling schizophrenia patients:a moderated mesomeric effect model[J].BMC Public Health,2024,24(1):1600-1609.
[21] 张银玲，史战明，赵科.居家病情稳定的精神分裂症患者攻击行为影响因素[J].国际精神病学杂志，2023，50(5):1190-1193.

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