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不同运动方式对冠心病患者心肺储备功能和运动耐力影响的网状Meta分析
作者:谢荣桂1  邓贵玉2  裴景茹1  唐云3  唐明明4  赵鸿5 
单位:1. 湖南中医药大学 护理学院, 湖南 长沙 410208;
2. 湖南中医药大学第一附属医院 中医经典科, 湖南 长沙 410007;
3. 湖南中医药大学第一附属医院 心内科, 湖南 长沙 410007;
4. 湖南中医药大学第一附属医院 眼科, 湖南 长沙 410007;
5. 湖南中医药大学第一附属医
关键词:冠心病 运动方式 心肺储备功能 运动耐力 网状Meta分析 
分类号:R541.4
出版年·卷·期(页码):2024·52·第十一期(1639-1651)
摘要:

目的: 系统评价不同运动方式对冠心病患者心肺储备功能和运动耐力的效果。方法: 检索中国知网(CNKI)、万方数据知识服务平台(Wanfang Data)、维普网(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Web of Science、The Cochrane Library、Embase数据库中关于运动方式改善冠心病患者心肺储备功能和运动耐力的随机对照研究,检索时间为建库至2023年4月。由2名研究者独立筛选文献、提炼资料和评价纳入文献的偏倚风险后,选择RevMan 5.3、Stata 16.0、R4.2.2进行统计分析。结果: 共纳入30项研究,2 433例冠心病患者,网状Meta分析结果显示:在提高左室射血分数(left ventricular ejection fraction, LVEF)方面,最好的2种运动方式是有氧结合抗阻运动和有氧运动;在提高6分钟步行试验(six minutes walk test, 6MWT)距离方面,最好的2种运动方式是抗阻运动和有氧结合抗阻运动;在改善肺功能方面,最好的2种运动方式是抗阻运动和瑜伽。但由于纳入研究的质量和数量等存在一定的局限性,仍需高质量研究进一步验证。结论: 运动可以改善冠心病患者的心肺储备功能和运动耐力,但不同运动改善心功能的侧重点不同,其中有氧结合抗阻运动在提高LVEF和6MWT方面效果最显著,抗阻运动在提高6MWT和FEV1/FVC%方面效果较好。

Objective: To systematically evaluate the effects of different exercise on cardiopulmonary reserve function and exercise endurance in patients with coronary heart disease. Methods: A randomized controlled study was searched from the databases of China National Knowledge Infrastructure(CNKI), Wanfang Data Knowledge Service Platform(Wanfang Data), VIP, SinoMed, PubMed, Web of Science, The Cochrane Library, and Embase on improving cardiovascular reserve function and exercise endurance in patients with coronary heart disease through exercise methods. The search was conducted from inception through April 2023. After two researchers independently screened the literature, extracted data, and evaluated the risk of bias in the included literature, RevMan 5.3, Stata16.0, and R4.2.2 were selected for statistical analysis. Results: A total of 30 studies were included, with 2 433 patients with coronary heart disease. The results of a network Meta-analysis showed that in terms of improving LVEF, the best 2 exercise modes were aerobic combined with resistance exercise and aerobic exercise; the two best exercise methods for increasing 6MWT were resistance exercise and aerobic combined resistance exercise; in terms of improving lung function, the two best exercise methods were resistance exercise and yoga. However, due to limitations in the quality and quantity of studies included, high-quality research is still needed for further validation. Conclusion: Exercise can improve cardiovascular reserve function and exercise endurance in patients with coronary heart disease, but the focus of different exercises on improving heart function varies, among which, aerobic combined with resistance exercise has the most significant effect on improving LVEF and 6MWT, while resistance exercise has a better effect on improving 6MWT and FEV1/FVC%.

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