目的： 调查肛肠手术患者术后疲劳认知现状及分析其影响因素。方法： 选取本院2019年9月—2023年9月收治的接受肛肠手术术后疲劳患者280例，分析肛肠手术患者术后疲劳的影响因素及其与术后疲劳的相关性。结果： 重度组年龄、性别、文化程度、医疗费用来源、术后并发症、吸烟占比及VAS、PSQI以及POMS-SF量表评分均高于轻度组(P＜0.05)；中度组各指标均高于轻度组(P＜0.05)；年龄、术后并发症、VAS、PSQI、POMS-SF评分高均是肛肠手术患者术后疲劳的影响因素(P＜0.05)；年龄、术后并发症、VAS、PSQI、POMS-SF评分与肛肠手术患者术后疲劳程度均呈正相关(P＜0.05)。结论： 年龄大、术后并发症发生、VAS、PSQI、POMS-SF高评分是肛肠手术患者发生术后疲劳的独立危险因素，其与术后疲劳程度呈正相关。

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