江苏省429名吸毒者梅毒和生殖道衣原体感染状况分析-现代医学

江苏省429名吸毒者梅毒和生殖道衣原体感染状况分析

作者：卢静¹ 胡海洋¹ 史灵恩¹ 王金塔² 朱正平³ 陈禹衡¹ 徐晓琴¹ 杨丹丹¹

单位：1. 江苏省疾病预防控制中心性病与艾滋病防制所, 江苏南京 210009;
2. 常州市疾病预防控制中心性病与艾滋病防制科, 江苏常州 213022;
3. 南京市疾病预防控制中心性病与艾滋病防制科, 江苏南京 210003

分类号：R759.1

出版年·卷·期（页码）：2024·52·第六期（926-931）

摘要：

目的： 了解江苏省吸毒者梅毒和生殖道衣原体(chlamydia trachomatis，CT)感染状况及可能的影响因素。方法： 2021年在江苏省南京市和常州市对新进入戒毒所的吸毒者进行问卷调查，并进行梅毒等血清学检测和CT等核酸检测，计算感染率；采用卡方检验和修正Poisson回归分析梅毒及生殖道CT感染可能的影响因素。结果： 共招募吸毒者429名，梅毒感染率为8.2%(95%CI 5.6%～10.7%)，生殖道CT感染率为2.1%(95%CI 0.7%～3.5%)。卡方检验结果显示，梅毒感染与最近一年接受过艾滋病(HIV)检测和HIV感染有关，生殖道CT感染与最近一年接受过HIV检测有关。多因素修正Poisson回归分析结果显示，40岁及以上、最近一年未接受过HIV检测、感染HIV的吸毒者更可能感染梅毒(P＜0.05)。结论： 江苏省吸毒者梅毒和生殖道CT感染率较高，应加强对这一人群性病筛查、诊断和治疗。

Objective: To investigate the prevalence of syphilis and Chlamydia trachomatis(CT) infection and their associated factors in drug users in Jiangsu Province. Methods: A cross-sectional survey was conducted among drug users who entered drug rehabilitation centers in Nanjing and Changzhou in Jiangsu Province in 2021. Sociodemographic characteristics and sexually transmitted infection(STI)-related behavioral information were collected through questionnaire interview. Venous blood specimens were collected for syphilis testing, and urine specimens were collected for CT testing. Chi-square test and modified Poisson regression were used to identify factors associated with syphilis and CT infection. Results: A total of 429 drug users were enrolled in the survey. The prevalence of syphilis and CT infection were 8.2% and 2.1%, respectively. Chi-square test results showed that syphilis infection was associated with HIV testing and HIV infection in the last year, and CT infection was associated with HIV testing in the last year. The results of multivariate modified Poisson regression analysis showed that drug users who were older than 40 years, did not have an HIV test in the past 12 months, and living with HIV were more likely to have syphilis infection.(P＜0.05). Conclusion: The infection rate of syphilis and genital chlamydia in drug users in Jiangsu Province is relatively high, so the screening, diagnosis and treatment of STD in this population should be strengthened.

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