[1] 罗从周,刘雨佳,陈俊.肿瘤相关巨噬细胞(TAMs):从基础到临床[J].中国免疫学杂志,2023,39(3):449-458.
[2] MANTOVANI A,SICA A,SOZZANI S,et al.The chemokine system in diverse forms of macrophage activation and polarization[J].Trends Immunol,2004,25(12):677-686.
[3] 张春焕,阚士锋,魏守娟,等.LPS通过宫颈癌细胞来源的IL-6调节巨噬细胞分泌和趋化活性[J].现代妇产科进展,2021,30(12):905-909.
[4] BISWAS S K,MANTOVINA A.Macrophage plasticity and interaction with lymphocyte subsets:cancer as a paradigm[J].Nat Immunol,2010,11(10):889-896.
[5] GOERDON S,MARTINEZ F O.Alternative activation of macrophages:mechanism and functions[J].Immunity,2010,32(5):593-604.
[6] SHILPAK C,ANANDA M,JAYATI M B,et al.A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells[J].PLoS One,2009,4(9):e7048.
[7] ZHANG F,WANG H S,WANG X F,et al.TGF-β induces M2-like macrophage polarization via SNAIL-mediatedsuppression of a pro-inflammatory phenotype[J].Oncotarget,2016,7(32):52294-52306.
[8] NGAMBENJAWONG C,GUSTAFSON H H,PUN S H.Progress in tumor-associated macrophage(TAM)-targeted therapeutics[J].Adv Drug Deliv Rev,2017,114:206-221.
[9] 柯星,张淑平,吴梦,等.肿瘤相关M2型巨噬细胞通过Toll样受体增强卵巢癌细胞MMP-9的表达[J].基础医学与临床,2014,34(10):1315-1320.
[10] 王方园,孔宪斌,杨玉莹,等.M2型TAMs激活NF-κB通路促进结肠癌细胞侵袭转移的实验研究[J].现代肿瘤医学.2020(21):3651-3656.
[11] 李睿.肠道微生物刺激组织蛋白酶K分泌介导TLR4依赖的M2巨噬细胞极化并促进结直肠癌转移 [D].广州:南方医科大学,2019.
[12] ZHENG P M,LUO Q,WANG W W,et al.Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional apolipoprotein E[J].Cell Death Dis,2018,9(4):434.
[13] 沈成全.乳酸重塑肿瘤相关巨噬细胞与膀胱癌细胞之间的交互作用促进TGF-β正反馈通路的机制研究[D].青岛:青岛大学,2021.
[14] 吴丽丽,孙慧誌,孙冉,等.缺氧诱导因子-1α对结直肠癌细胞上皮间质转化及侵袭迁移的影响[J].天津医药,2016,44(5):535-539,657-658.
[15] 刘明锐,赵洪瑜.抗血管生成药物在结直肠癌治疗中的应用进展[J].癌症进展,2022(7):664-667,679.
[16] 蔡秋莉,陈芸,蔡昕怡,等,结直肠腺癌中CD163+巨噬细胞、CD8+T细胞与微血管密度的相关性[J].肿瘤学杂志,2021(8):622-627.
[17] 郝汉霞,王水,刘力嘉,等.乳腺癌肿瘤相关巨噬细胞中HIF-2α/EPAS1表达与血管生成的关系[J].中华肿瘤防治杂志,2006(3):169-172.
[18] 杨春康,陈道达,张惠灏,等.结直肠癌趋化因子IL-8的表达与血管形成的关系[J].世界华人消化杂志,2005(7):899-901.
[19] 高双英,吴静,杨贵丽.结肠癌肿瘤相关巨噬细胞的浸润和MMP-2的表达、血管生成关系的研究[J].中国免疫学杂志,2016(3):336-339,344.
[20] 张静,胡哲,居红格.TAMs激活Src-RhoA通路上调免疫抑制因子表达及促进直肠癌细胞增殖和EMT[J].免疫学杂志,2021(7):596-603.
[21] 廉祎,黄瑛.肿瘤相关巨噬细胞参与肿瘤免疫调节的研究进展[J].解剖科学进展,2018(5):542-546.
[22] 林花,李雨涵,王云娜,等.肿瘤相关巨噬细胞促进肿瘤侵袭转移机制的研究进展[J].老年医学研究,2021,2(4):53-56.
[23] ANFRAY C,UMMARINO A,ANDON F T,et al.Current strategies to target tumor-associated-macrophages to improve anti-tumor immune responses[J].Cells,2019,9(1):46.
[24] YIN Y,YAO S,HU Y,et al.The Immune-microenvironment confers chemoresistance of colorectal cancer through macrophage-derived IL6[J].Clin Cancer Res,2017,23(23):7375-7387.
[25] WEI C,YANG C,WANG S,et al.M2 macrophages confer resistance to 5-fluorouracil in colorectal cancer through the activation of CCL22/PI3K/AKT signaling[J].Onco Targets Ther,2019,12:3051-3063.
[26] LI X,LIU R,SU X,et al.Harnessing tumor-associated macrophages as aids for cancer immunotherapy[J].Mol Cancer,2019,18(1):177.
[27] 秦叔逵,王锋.氯膦酸二钠防治恶性肿瘤骨转移临床应用专家共识[J].临床肿瘤学杂志,2020(1):64-74.
[28] 王宇驰.CSF-1R抑制剂载体的构建及靶向肿瘤相关巨噬细胞免疫治疗的研究[D].延边:延边大学,2021.
[29] 张解放,薛洪峰,王茂峰,等.趋化因子CCL2在结直肠癌组织中的表达及其作用机制[J].中华普通外科杂志,2018,33(7):589-591.
[30] 郭春光,刘骞,孙力超,等.CCL2表达与同时性结直肠癌肝转移的相关性分析[J].中华结直肠疾病电子杂志,2015(3):254-259.
[31] 周明利,卢先州,张留柱,等.基因沉默HIF-1α在结直肠癌SW480细胞的缺氧与上皮-间质转化中的作用[J].实用肿瘤杂志,2012(3):226-232.
[32] 朱东明,李德春.缺氧诱导因子2与缺氧诱导因子1对胰腺癌中血管内皮生长因子表达的作用[C].//苏州市自然科学优秀学术论文汇编(2008-2009).[出版者不详],2010:160.
[33] 谷化平,尚培中.EGFR、VEGF和PTEN在结直肠癌中表达及与其临床病理特征的关系[J].实用癌症杂志,2011,26(3):259-262.
[34] 李腾飞,黄陈.肿瘤间质成分在结直肠癌中的研究现状及进展[J].中华结直肠疾病电子杂志,2020(5):447-452.
[35] HU Y,HE Y,LIU W,et al.SIAH2 regulates colorectal cancer tumorigenesis via PI3K/ATK signaling pathway[J].Tissue Cell,2022,78:101878.
[36] LIU C,ZHANG W,WANG J,et al.Tumor associated macrophages derived TGF-β promotes colorectal cancer progression through HIF1-TRIB3 signaling[J].Cancer Sci,2021,112(10):4198-4207.
[37] 谢昌利,刘翠颖,林艳,等.IRF1对M1巨噬细胞极化及其抗肿瘤效应的影响[J].基础医学与临床,2017,37(2):189-196.
[38] 苏小薇,吴波,孙海梅,等.胶原蛋白具有促进肿瘤相关巨噬细胞向M1型极化的作用[J].解剖学报,2019(4):445-450.
[39] ASHOK K,SALMA I,ANANDA M,et al.TLR-2,TLR-3 and TLR-4 agonists induce synthesis of IFN-gamma in human M1 but not in M2a,M2b and M2c macrophages through the activation of S6K1-S6 pathway[J].J Immunol,2019,202(sup):64.23.
[40] 刘志鹏.TLR7/8激动剂通过调节MDSCs向M1型巨噬细胞分化增强奥沙利铂在结直肠癌中的化疗疗效[D].广州:南方医科大学,2020.
[41] 杨颖,李勤,郭忠慧,等.M-CSF、GM-CSF诱导人源外周血单个核细胞来源巨噬细胞的不同极化和吞噬[J].中国输血杂志,2020,33(9):859-864.
[42] 王珍,茅芯慧,章恒,等.STAT3诱导巨噬细胞M2型极化促进宫颈癌细胞的放疗抵抗及机制研究[J].现代肿瘤医学,2022(15):2710-2715.
[43] WANG D,WANG X,SI M,et al.Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages[J].Cancer Lett,2020,474:36-52.
[44] LAI F,ZHANG H,XU B,et al.Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM[J].Bioengineered,2021,12(1):5462-5475. |