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常州在校藏族学生中结核分枝杆菌强阳性潜伏感染状况调查
作者:张兴1  李晨2  冯彬3  吴玉姣4  邬银燕5  陈彦妃6  左小明4 
单位:1. 常州市疾病预防控制中心 慢性传染病防治科, 江苏 常州 213003;
2. 南京市疾病预防控制中心 慢性传染病防治科, 江苏 南京 210003;
3. 南京医科大学 公共卫生学院, 江苏 南京 211166;
4. 常州市第三人民医院 药事科, 江苏 常州 213001;
5. 常州市钟楼区疾病预防
关键词:结核菌潜伏感染 藏族学生 影响因素 
分类号:R181.3
出版年·卷·期(页码):2024·52·第四期(581-586)
摘要:

目的:了解常州地区藏族初高中学生结核潜伏感染(LTBI)的流行现状,为探索学校内高负担地区学生的结核病管理以及实施防控措施提供依据。 方法:采用结核分枝杆菌素纯化蛋白衍生物(PPD)皮内注射法(Mantoux法)进行结核菌潜伏感染检测,收集2023年常州市西藏民族中学和奔牛高中两所学校内的藏族学生进行筛查获得相关资料,并进行统计描述。 结果:本次筛查共调查500例,获得480份有效数据,有效率为96%。共筛查出PPD强阳性学生58例,强阳性率12.08%。男性PPD强阳性率高于女性,农村学生PPD阳性率较高,有既往结核病史的学生筛查出PPD强阳性率高于既往无结核病史的学生,差异具有统计学意义(P<0.05)。结论:藏族学生的结核病潜伏感染负担较重,应将结核病高发地区的学生作为筛查的重点对象。

Objective: To investigate the prevalence of latent tuberculosis infection(LTBI) among middle and high school Tibetan students in Changzhou, and to provide evidence for the management of tuberculosis in high burden areas and the implementation of prevention and control measures. Methods: Mycobacterin purified protein derivative(PPD) intradermal injection method(Mantoux method) was used to detect latent tuberculosis infection,collect Tibetan students' relevant data from 2 schools in Changzhou in 2023,and describe the data statistically. Results:This investigation involved 500 people, 480 valid data were obtained, with an effective rate of 96%. A total of 58 students were found to be strongly positive for PPD, with a strong positive rate of 12.08%. The strong positive rate of PPD in males was higher than that in females, and the positive rate of PPD in rural students was lower,students with a history of tuberculosis had a higher positive rate of PPD than students without a history of tuberculosis(P<0.05). Conclusion: Tibetan students have a heavy burden of latent TB infection, and students in areas with high incidence of TB should be selected as the key targets for screening.

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