目的：探讨针灸推拿联合自制中药治疗中老年人神经根型颈椎病的临床效果。方法：以2019—2022年在某医院接受中医治疗的147例中老年人神经根型颈椎病患者作为研究对象，按照简单随机分组的方法将研究对象分为对照组和观察组，对照组采取常规针灸推拿治疗，观察组患者在常规的针灸推拿基础上联合自制的中药治疗。采用t检验、卡方检验或秩和检验分析比较两组治疗前后颈椎功能指标、实验室炎症指标、心理状态评估及满意度。结果：治疗后，观察组有效和显效的比例为94.36%，高于对照组的86.84%(P=0.040)；治疗后，观察组颈椎功能障碍指数(NDI)、视觉模拟评分(VAS)降低幅度均大于对照组(P＜0.001)；与治疗前比较，观察组患者血清C反应蛋白(CRP)、白介素-6(IL-6)、前列腺素E2(PGE₂)、5-羟色胺(5-HT)等指标的降低幅度明显大于对照组(P<0.001)；治疗过程中，两组不良反应发生率之间比较，差异无统计学意义(χ²=0.19，P=0.666)；干预后3个月，观察组症状自评量表-90项(SCL-90)总分为(140.20±4.55)分，低于对照组的(157.00±5.28)分(P＜0.001)；出院时，观察组患者对治疗、健康教育及治疗结局的满意度得分明显高于对照组(P＜0.05)。结论:针灸推拿联合中药治疗中老年人神经根型颈椎病可有效缓解患者颈椎疼痛，降低机体炎症因子和疼痛介质表达，改善患者生活质量，提高患者的满意度。

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