[1] BERENBAUM S A,BELTZ A M.Sexual differentiation of human behavior:effects of prenatal and pubertal organizational hormones[J].Front Neuroendocrinol,2011,32(2):183-200.
[2] ALGHAMDI A.Precocious puberty:types,pathogenesis and updated management[J].Cureus,2023,15:e47485.
[3] CHEN L,SHI G R,HUANG D D,et al.Male sexual dysfunction:a review of literature on its pathological mechanisms,potential risk factors,andherbal drug intervention[J].Biomed Pharmacother,2019,112:108585.
[4] RAMALHO-SANTOS J,VARUM S,AMARAL S,et al.Mitochondrial functionality in reproduction:from gonads and game tes to embryos and embryonic stem cells[J].Hum Reprod Update,2009,15(5):553-72.
[5] LANCIOTTI L,COFINI M,LEONARDI A,et al.Up-to-date review about minipuberty and overview on hypothalamic-pituitary-gonadal axis activation in fetal and neonatal life[J].Front Endocrinol,2018,9:410.
[6] PERRY R J,FARQUHARSON C,AHMED S F.The role of sex steroids in controlling pubertal growth[J].Clin Endocrinol,2007,68(1):4-15.
[7] KUIRI-HANNINEN T,SANKILAMPI U,DUNKEL L.Activation of the hypothalamic-pituitary-gonadal axis in infancy:minipuberty[J].Horm Res Paediatr,2014,82(2):73-80.
[8] TERASAWA E,FERNANDEZ D L.Neurobiological mechanisms of the onset of puberty in primates[J].Endocr Rev,2001,22(1):111-151.
[9] SPEROFF,LEON F,MARC A.Clinical gynecologic endocrinology and infertility[M] Philadelphia:Lippincott Williams & Wilkins,2005.
[10] The Subspecialty Group of Endocrinologic Hamd,The Society of Pediatrics,Chinese Medical Association,The Editorial Board.Expert consensus on the diagnosis and treatment of central precocious puberty(2022)[J].Chinese journal of pediatrics,2023,61(1):16-22.
[11] CHEN M,EUGSTER E A.Central precocious puberty:update on diagnosis and treatment[J].Pediatric Drugs,2015,17(4):273-281.
[12] LATRONICO A C,BRITO V N,CAREL J C.Causes,diagnosis,and treatment of central precocious puberty[J].Lancet Diabetes Endocrinol,2016,4(3):265-274.
[13] KAPLOWITZ P,BLOCH C,SILLS I N,et al.Evaluation and referral of children with signs of early puberty[J].Pediatrics,2016,137(1).
[14] BANGALORE KRISHNA K,FUQUA J S,ROGOL A D,et al.Use of gonadotropin-releasing hormone analogs in children:update by an international consortium[J].Horm Res Paediatr,2019,91(6):357-372.
[15] CAREL J C,EUGSTER E A,ROGOL A,et al.Consensus statement on the use of gonadotropin-releasing hormone analogs in children[J].Pediatrics,2009,123(4):e752-e762.
[16] PARENT A S,RASIER G,GERARD A,et al.Early onset of puberty:tracking genetic and environmental factors[J].Horm Res,2005,64(Suppl 2):41-47.
[17] SCHOETERS G,DEN HOND E,DHOOGE W,et al.Endocrine disruptors and abnormalities of pubertal development[J].Basic Clin Pharmacol Toxicol,2008,102(2):168-175.
[18] NACCARATO A G,VIACAVA P,VIGNATI S,et al.Bio-morphological events in the development of the human female mammary gland from fetal age to puberty[J].Virchows Arch,2000,436(5):431-438.
[19] COLVIN C W,ABDULLATIF H.Anatomy of female puberty:the clinical relevance of developmental changes in the reproductive system[J].Clin Anat,2013,26(1):115-129.
[20] BRITO V N,LATRONICO A C,ARNHOLD I J,et al.Update on the etiology,diagnosis and therapeutic management of sexual precocity[J].Arq Bras Endocrinol Metabol,2008,52(1):18-31.
[21] LEE P A.Laboratory monitoring of children with precocious puberty[J].Arch Pediatr Adolesc Med,1994,148(4):369-376.
[22] CESARIO S K,HUGHES L A.Precocious puberty:a comprehensive review of literature[J].J Obstet Gynecol Neonatal Nurs,2007,36(3):263-274.
[23] BRITO V N,BATISTA M C,BORGES M F,et al.Diagnostic value of fluorometric assays in the evaluation of precocious puberty[J].J Clin Endocrinol Metab,1999,84(10):3539-3544.
[24] FREIRE A V,ESCOBAR M E,GRYNGARTEN M G,et al.High diagnostic accuracy of subcutaneous triptorelin test compared with GnRH test for diagnosing central precocious puberty in girls[J].Clin Endocrinol(Oxf),2013,78(3):398-404.
[25] PALMERT M R,HIRSCHHORN J N.Genetic approaches to stature,pubertal timing,and other complex traits[J].Mol Genet Metab,2003,80(1-2):1-10.
[26] TOWNE B,CZERWINSKI S A,DEMERATH E W,et al.Heritability of age at menarche in girls from the fels longitudinal study[J].Am J Phys Anthropol,2005,128(1):210-219.
[27] VAN DEN BERG S M,BOOMSMA D I.The familial clustering of age at menarche in extended twin families[J].Behav Genet,2007,37(5):661-667.
[28] LEKA-EMIRI S,CHROUSOS G P,KANAKA-GANTENBEIN C.The mystery of puberty initiation:genetics and epigenetics of idiopathic central precocious puberty(ICPP)[J].J Endocrinol Invest,2017,40(8):789-802.
[29] CHEN C,ZHANG Y,SUN W,et al.Investigating the relationship between precocious puberty and obesity:a cross-sectional study in Shanghai,China[J].BMJ Open,2017,7(4):e014004.
[30] HONG Y H,WOO Y J,LEE J H,et al.Association between dietary habits and parental health with obesity among children with precocious puberty[J].Children,2020,7(11):220.
[31] BARTHA J L,MARÍN-SEGURA P,GONZÁLEZ-GONZÁLEZ N L,et al.Ultrasound evaluation of visceral fat and metabolic risk factors during early pregnancy[J].Obesity(Silver Spring),2007,15:2233-2239.
[32] WANG M,ZHANG Y,MILLER D,et al.Microbial reconstitution reverses early female puberty induced by maternal high-fat diet during lactation[J].Endocrinology,2020,161(2):bqz041.
[33] ULLAH R,SU Y,SHEN Y,et al.Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups:a novel model of obesity and puberty[J].Front Med,2017,11(2):266-276.
[34] LIE M E,OVERGAARD A,MIKKELSEN J D.Effect of a postnatal high-fat diet exposure on puberty onset,estrous cycle regularity,and kisspeptin expression in female rats[J].Reprod Biol,2013,13(4):298-308.
[35] TAKUMI K,SHIMADA K,IIJIMA N,et al.Maternal high-fat diet during lactation increases Kiss1 mRNA expression in the arcuate nucleus at weaning and advances puberty onset in female rats[J].Neurosci Res,2015,100:21-28.
[36] DENG F,TAO F B,LIU D Y,et al.Effects of growth environments and two environmental endocrine disruptors on children with idiopathic precocious puberty[J].Eur J Endocrinol,2012,166(5):803-809.
[37] LEE J H,MIELE M E,HICKS D J,et al.Kiss-1,a novel human malignant melanoma metastasis-suppressor gene[J].J Natl Cancer Inst,1996,88(23):1731-1737.
[38] GUTIERREZ-PASCUAL E,MARTINEZ-FUENTES A J,PINILLA L,et al.Direct pituitary effects of kisspeptin:activation of gonadotrophs and somatotrophs and stimulation of luteinising hormone and growth hormone secretion[J].J Neuroendocrinol,2007,19(7):521-530.
[39] OHTAKI T,SHINTANI Y,HONDA S,et al.Metastasis suppressor gene Kiss-1 encodes peptide ligand of a G-protein-coupled receptor[J].Nature,2001,411(6837):613-617.
[40] LEÓN S,BARROSO A,VÁZQUEZ M J,et al.Direct actions of kisspeptins on GnRH neurons permit attainment of fertility but are insufficient to fully preserve gonadotropic axis activity[J].Sci Rep,2016,6(1):19206.
[41] BARROSO A,ROA J,TENA-SEMPERE M.Neuropeptide control of puberty:beyond kisspeptins[J].Semin Reprod Med,2020,37(04):155-165.
[42] LOMNICZI A,LOCHE A,CASTELLANO J M,et al.Epigenetic control of female puberty[J].Nat Neurosci,2013,16(3):281-289.
[43] NAVARRO V M.New insights into the control of pulsatile GnRH release:the role of Kiss1/neurokinin B neurons[J].Front Endocrinol(Lausanne),2012,3:48.
[44] PREVOT V,HANCHATE N K,BELLEFONTAINE N,et al.Function-related structural plasticity of the GnRH system:a role for neuronal-glial-endothelial interactions[J].Front Neuroendocrinol,2010,31(3):241-258.
[45] BARROSO A,ROA J,TENA-SEMPERE M.Neuropeptide control of puberty:beyond kisspeptins[J].Semin Reprod Med,2019,37(4):155-165.
[46] RHIE Y J,LEE K H,EUN S H,et al.Serum kisspeptin levels in Korean girls with central precocious puberty[J].J Korean Med Sci,2011,26(7):927-931.
[47] MACEDO D B,ABREU A P,REIS A C,et al.Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3[J].J Clin Endocrinol Metab,2014,99(6):E1097-E1103.
[48] BUTLER M G.Genomic imprinting disorders in humans:a mini-review[J].J Assist Reprod Genet,2009,26(9-10):477-486.
[49] SORIANO-GUILLEN L,ARGENTE J.Central precocious puberty,functional and tumor-related[J].Best Pract Res Clin Endocrinol Metab,2019,33(3):101262.
[50] ABREU A P,DAUBER A,MACEDO D B,et al.Central precocious puberty caused by mutations in the imprinted gene MKRN3[J].N Engl J Med,2013,368(26):2467-2475.
[51] LI C,LU W,YANG L,et al.MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3[J].Natl Sci Rev,2020,7(3):671-685.
[52] BANGALORE KRISHNA K,FUQUA J S,ROGOL A D,et al.Use of gonadotropin-releasing hormone analogs in children:update by an international consortium[J].Horm Res Paediatr,2019,91(6):357-372.
[53] VURALLI D,GONC N E,OZON Z A,et al.Which parameters predict the beneficial effect of GnRHa treatment on height in girls with central precocious puberty?[J].Clin Endocrinol,2021,94(5):804-810.
[54] SANCTIS V D,SOLIMAN A T,MAIO S D,et al.Long-term effects and significant adverse drug reactions(ADRs) associated with the use of gonadotropin-releasing hormone analogs(GnRHa) for central precocious puberty:a brief review of literature[J].Acta Biomed,2019,90(3):345-359.
[55] TAO Y,SI C,LI H,et al.Effect of gonadotropin-releasing hormone analog on ovarian reserve in children with central precocious puberty[J].Ann Palliat Med,2020,9(1):53-62.
[56] ALESSANDRI S B,PEREIRA FDE A,VILLELA R A,et al.Bone mineral density and body composition in girls with idiopathic central precocious puberty before and after treatment with a gonadotropin-releasing hormone agonist[J].Clinics(Sao Paulo),2012,67(6):591-596.
[57] 国家药品监督管理局.药物警戒快讯[Z].2022.JSXX-2022-106.
[58] LIN S,YANG W Q,YU J.Guidelines for clinical diagnosis and treatment in pediatrics of traditional chinese medicine[J].J Pediatr Tradit Chin Med,2016,12(3):1-5.
[59] YEUNG A W K,HEINRICH M,KIJJOA A,et al.The ethnopharmacological literature:an analysis of the scientific landscape[J].J Ethnopharmacol,2020,250:112414.
[60] SHI G J,ZHENG J,WU J,et al.Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice[J].Food Funct,2017,8(3):1215-1226.
[61] LIN Y C,CHANG T T,CHEN H J,et al.Characteristics of traditional chinese medicine usage in children with precocious puberty:a nationwide population-based study[J].J Ethnopharmacol,2017,205:231-239.
[62] 赵倩,霍宇,姜蔚.知柏地黄丸的药理作用和临床应用研究进展[J].中国医药,2022,17(11):1752-1756.
[63] 孙丽英,于秋爽,高微,等.中医药治疗儿童性早熟的研究述评[J].中医药信息,2012,29(1):138-140.
[64] 王静,邢向晖.中医药治疗儿童性早熟的研究述评[J].中医药学刊,2003,21(11):1870-1871.
[65] 徐佩莉,兰志建.知柏地黄加减方对性早熟及青春期发育进程过快女童子宫、卵巢的影响[J].中国中医药科技,2012,19(2):184-185.
[66] 周小平.知柏地黄丸加减治疗阴虚火旺型特发性中枢性性早熟女童的回顾性研究[D].武汉：湖北中医药大学,2022.
[67] SIROTKIN A V,STOCHMALOVA A,ALEXA R,et al.Quercetin directly inhibits basal ovarian cell functions and their response to the stimulatory action of FSH[J].Eur J Pharmacol,2019,860:172560.
[68] LIN Y Y,JAN Y.Research advances in estrogen receptors and pubertal development[J].J Tradit Chin Med,2012,27(12):3176-3178.
[69] LEE H Y,LEE Y J,AHN M B,et al.The effect of overweight on the luteinizing hormone level after gonadorelin stimulation test in girls with idiopathic central precocious puberty[J].Ann Pediatr Endocrinol Metab,2018,23(4):215-219.
[70] ZHENG Z G,ZHOU Y P,ZHANG X,et al.Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation[J].Biochem Pharmacol,2016,122:42-61.
[71] AKISON L K,ROBKER R L.The critical roles of progesterone receptor(PGR) in ovulation,oocyte developmental competence and oviductal transport in mammalian reproduction[J].Reprod Domest Anim,2012,47(Suppl 4):288-296.
[72] 蔡德培,张炜.补肾中药对下丘脑GnRH、垂体FSH、LH及成骨细胞BGP基因表达的调节作用[J].中医杂志,2002,43(3):221-223.
[73] 蔡德培,陈伯英,庄振杰.滋阴泻火中药对下丘脑GnRH的合成、分泌及其调节机制的影响[J].中国中西医结合杂志,2001,(8):595-598. |
