1990—2019年中国归因于高BMI的非传染性疾病死亡趋势的年龄-时期-队列分析-现代医学

1990—2019年中国归因于高BMI的非传染性疾病死亡趋势的年龄-时期-队列分析

单位：首都医科大学附属北京康复医院劳模健康管理中心, 北京 100144

分类号：R54,R73

出版年·卷·期（页码）：2024·52·第三期（435-440）

摘要：

目的：分析1990至2019年中国归因于高身体质量指数(BMI)的非传染性疾病(NCDs)死亡率的长期趋势，为中国NCDs的管理提供科学依据。方法：从全球疾病负担数据库2019(GBD 2019)获取1990至2019年中国归因于高BMI的NCDs的死亡负担数据，使用年龄-时期-队列模型评估中国归因于高BMI的NCDs的年龄、时期、队列效应。结果：1990至2019年中国归因于高BMI的NCDs标化死亡率呈上升趋势，总人口从29.80/10万增至40.55/10万，其中男性从30.91/10万增至49.10/10万，女性从28.82/10万增至33.20/10万。年龄-时期-队列模型分析显示，年龄效应均呈现上升趋势；总人口、男性的时期效应和队列效应均呈现上升趋势，而女性呈现下降趋势。中国归因于高BMI的6种NCDs的死亡负担中，位于前3位的分别为血管疾病、肿瘤以及糖尿病和肾脏疾病。结论：1990—2019年，中国归因于高BMI的NCDs的死亡负担呈上升趋势，需重点加强50岁以上的男性人群干预，指导居民进行体重管理。

Objective: To analyze the secular trends of noncommunicable diseases(NCDs) mortality attribute to high body mass index(BMI) in China from 1990 to 2019, and to provide scientific evidence for NCDs management in China.Methods: Data on the death burden of NCDs attribute to high BMI in China from 1990 to 2019 were obtained from Global Burden of Disease Database 2019(GBD 2019). Age-period-cohort model was used to estimate the effects of age, period and cohort on NCDs attribute to high BMI.Results: The standardized mortality rate of NCDs due to high BMI in China increased from 1990 to 2019, with the total population increased from 29.80/10⁵ to 40.55/10⁵, of which male increased from 30.91/10⁵to 49.10/10⁵, and female increased from 28.82/10⁵to 33.20/10⁵. Age-period-cohort model analysis showed that the age effect showed an increasing trend. The total population, males's period and cohort effects all showed an increasing trend, while a decreasing trend in females. The top three death burden of six NCDs attribute to high BMI in China were vascular disease, tumor, diabetes and kidney disease.Conclusion: From 1990 to 2019, the death burden of NCDs attribute to high BMI is on the rise in China. It is necessary to strengthen the intervention in men over 50 years old and guide the residents to carry out weight management.

参考文献：

[1] GBD 2019 Diseases and Injuries Collaborators.Global burden of 369 diseases and injuries in 204 countries and territories,1990—2019:a systematic analysis for the Global Burden of Disease Study 2019[J].Lancet,2020,396(10258):1204-1222.
[2] Word Health Organization.The top 10 causes of death[EB/OL].Last 2018.https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.
[3] GBD 2019 Diseases and Injuries Collaborators.Global,regional,and national age-sex-specific mortality for 282 causes of death in 195 countries and territories,1980-2017:a systematic analysis for the global burden of disease study 2017[J].Lancet,2018,392(10159):1736-1788.
[4] ZHOU M,WANG H,ZENG X,et al.Mortality,morbidity,and risk factors in China and its provinces,1990-2017:a systematic analysis for the global burden of disease study 2017[J].Lancet,2019,394(10204):1145-1158.
[5] GATI A,KOUIDHI S,MARRAKCHI R,et al.Obesity and renal cancer:role of adipokines in the tumor-immune system conflict[J].Oncoimmunology,2014,3(1):e27810.
[6] SOLAREK W,CZARNECKA A M,ESCUDIER B,et al.Insulin and IGFs in renal cancer risk and progression[J].Endocr Relat Cancer,2015,22(5):253-264.
[7] DAI H,ALSALHE T A,CHALGHAF N,et al.The global burden of disease attributable to high body mass index in 195 countries and territories,1990-2017:an analysis of the global burden of disease study[J].PLoS Medicine,2020,17(7):e1003198.
[8] SUN X,LIU Z,DU T.Secular trends in the prevalence of abdominal obesity among Chinese adults with normal weight,1993-2015[J].Sci Rep,2021,11(1):16404.
[9] TIAN Y,JIANG C,WANG M,et al.BMI,leisure-time physical activity,and physical fitness in adults in China:results from a series of national surveys,2000-14[J].Lancet Diabetes Endocrinol,2016,4(6):487-497.
[10] 李立明,饶克勤,孔灵芝,等.中国居民2002年营养与健康状况调查[J].中华流行病学杂志,2005,26(7):478-484.
[11] ZENG Q,LI N,PAN X F,et al.Clinical management and treatment of obesity in China[J].Lancet Diabetes Endocrinol,2021,9(6):393-405.
[12] BAI R,WU W,DONG W,et al.Forecasting the populations of overweight and obese chinese adults[J].Diabetes Metab Syndr Obes,2020,13:4849-4857.
[13] GBD 2019 Risk Factors Collaborators.Global burden of 87 risk factors in 204 countries and territories,1990—2019:a systematic analysis for the global burden of disease study 2019[J].Lancet,2020,396(10258):1223-1249.
[14] NAGHAVI M,MAKELA S,FOREMAN K,et al.Algorithms for enhancing public health utility of national causes-of-death data[J].Popul Health Metr,2010,21(3):8-9.
[15] 张嫣然,宇传华,胡迪,等.1990―2019年中国归因于水果摄入不足的食管癌死亡趋势[J].中华疾病控制杂志,2023,27(1):4-10.
[16] GU H,SHAO S,LIU J,et al.Age-and sex-associated impacts of body mass index on stroke type risk:a 27-year prospective cohort study in a low-income population in China[J].Front Neurol,2019,10:456.
[17] FLORESCU A,BRANISTEANU D,BILHA S,et al.Leptin and adiponectin dynamics at patients with rectal neoplasm-gender differences[J].PLoS One,2019,14(8):e0212471.
[18] DIKAIOU P,BJÖRCK L,ADIELS M,et al.Obesity,overweight and risk for cardiovascular disease and mortality in young women[J].Eur J Prev Cardiol,2021,28(12):1351-1359.
[19] POLOZ Y,STAMBOLIC V.Obesity and cancer,a case for insulin signaling[J].Cell Death Dis,2015,6(12):e2037.
[20] 魏改云,何伟,吕全军,等.某中青年体检人群体成分与血胰岛素水平相关分析[J].现代医学,2017,45(8):1149-1154.
[21] WANG Y,PENG Q,GUO J,et al.Age-period-cohort analysis of type-specific stroke morbidity and mortality in China[J].Circulation,2020,84(4):662-669.
[22] LEI S,ZHENG R,ZHANG S,et al.Breast cancer incidence and mortality in women in China:temporal trends and projections to 2030[J].Cancer Biol Med,2021,18(3):900-909.
[23] WANG Z,HU S,SANG S,et al.Age-period-cohort analysis of stroke mortality in China:data from the global burden of disease study 2013[J].Stroke,2017,48(2):271-275.
[24] LI X,SONG J,LIN T,et al.Urbanization and health in China,thinking at the national,local and individual levels[J].Environ Health,2016,15(Suppl 1):32.
[25] WANG Y J,LI Z X,GU H Q,et al.China stroke statistics 2019:a report from the national center for healthcare quality management in neurological diseases[J].Stroke Vasc Neurol,2020,5(3):211-239.
[26] WANG Z,ZHENG R.Impact of cigarette smoking on the relationship between body mass index and coronary heart disease:a pooled analysis of 3264 stroke and 2706 CHD events in 378579 individuals in the Asia Pacific region[J].BMC Public Health,2009,9(3):294-301.
[27] WANG M,LUO X,XU S,et al.Trends in smoking prevalence and implication for chronic diseases in China:serial national cross-sectional surveys from 2003 to 2013[J].Lancet Respir Med,2019,7(1):35-45.
[28] PAN X F,WANG L,PAN A.Epidemiology and determinants of obesity in China[J].Lancet Diabetes Endocrinol,2021,9(6):373-392.
[29] CAI L,HAN X,QI Z,et al.Prevalence of overweight and obesity and weight loss practice among Beijing adults,2011[J].PLoS One,2014,9(9):e98744.
[30] NICOLAOU M,DOAK C,DAM R,et al.Body size preference and body weight perception among two migrant groups of non-Western origin[J].Public Health Nutr,2008,11(12):1332-1341.

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