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血脂异常对南京市社区2型糖尿病患者血糖控制的影响
作者:张皓1  王志勇2  胡彩红2  刘蒙利2  张璇2  郑志丹1 
单位:1. 南京市中心医院 河西门诊部管理办公室, 江苏 南京 210008;
2. 南京市疾病预防控制中心 基本公共卫生 服务技术指导办公室, 江苏 南京 210003
关键词:血脂异常 血糖控制 社区2型糖尿病患者 
分类号:R587.1
出版年·卷·期(页码):2024·52·第二期(265-271)
摘要:

目的:了解血脂异常对南京市社区2型糖尿病患者血糖控制的影响。方法:采用多阶段分层整群抽样方法,随机抽取南京市18岁以上社区糖尿病患者5 663例作为研究对象,采用多因素Logistic回归分析血脂异常对糖尿病患者血糖控制的作用。结果:5 663例糖尿病患者空腹血糖控制率为39.8%(95%CI 38.5%~41.1%),其中血脂正常患者控制率为43.5%(95%CI 41.6%~45.4%),血脂异常患者控制率为36.6%(95%CI 34.9%~38.3%)。经调整年龄、性别、城乡、受教育水平、职业、高血压、吸烟、饮酒、体质指数、体力活动、糖尿病家族史和规律服药后,血脂异常患者空腹血糖控制率是血脂正常者的0.70倍(95%CI 0.62~0.79,P<0.001)。进一步按性别、城乡和是否规律使用降糖药分层分析显示,各亚组分析结果与总体情况一致。结论:血脂异常会降低社区2型糖尿病患者的血糖控制达标率。

Objective: To investigate the association between dyslipidemia and glycemic control among community patients with type 2 diabetes. Methods: Totally 5 663 community patients with type 2 diabetes(T2D) were randomly selected from urban and rural communities by multi-stage stratified cluster random sampling. Multivariable Logistic regression models were employed to estimate the associations between dyslipidemia and glycemic control among T2D patients. Results: The glycemic control rate was 39.8%(95%CI 38.5%-41.1%), while that of T2D patients with normal blood lipid and T2D patients with dyslipidemia were 43.5%(95%CI 41.6%-45.4%), 36.6%(95%CI 34.9%-38.3%), respectively. After adjustment for potential confounders such as age, gender, residence etc, T2D patients with dyslipidemia were at 0.70(95%CI 0.62-0.79, P<0.001) times odds to have glycaemia under control than patients with normal blood lipid. Furthermore, when stratified separately by gender, residence and use of anti-diabetes agents, Similar outcomes were observed from all sub-groups. Conclusion: Dyslipidemia might have a negative effect on glycemic control among T2D patients in Nanjing China.

参考文献:

[1] International Diabetes Federation.IDF diabetes atlas,10th ed,in IDF diabetes atlas[M].Brussels:International Diabetes Federation,2021:30-34.
[2] WANG L,PENG W,ZHAO Z,et al.Prevalence and treatment of diabetes in China,2013-2018[J].Jama,2021,326(24):2498-2506.
[3] HU C,JIA W.Diabetes in China:epidemiology and genetic risk factors and their clinical utility in personalized medication[J].Diabetes,2018,67(1):3-11.
[4] RODRIGUEZ R,MILLAN J M,BARRERA F J,et al.Value of patient-centered glycemic control in patients with type 2 diabetes[J].Curr Diab Rep,2021,21(12):63.
[5] NATHAN D M,The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years:overview[J].Diabetes Care,2014,37(1):9-16.
[6] 徐亮,杨松,陈燕春,等.血糖控制水平对糖尿病患者冠状动脉微循环阻力指数的影响[J].东南大学学报(医学版),2018,37(2):315-319.
[7] ARTHA I,BHARGAH A,DHARMAWAN N K,et al.High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus[J].Vasc Health Risk Manag,2019,15:149-157.
[8] 别霖臻,娄培安,张盼,等.血脂异常和高血压对2型糖尿病患者血糖控制的交互作用[J].中华糖尿病杂志,2022,14(9):961-967.
[9] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)[J].中华糖尿病杂志,2021,13(4):315-409.
[10] 中华医学会.血脂异常基层诊疗指南(2019)[J].中华全科医师杂志,2019,18(5):406-416.
[11] XU F,HE J,WANG Z,et al.The relationship between socio-economic status and diagnosed Type 2 diabetes is changing with economic growth in Nanjing,China[J].Diabet Med 2018,35(5):567-575
[12] World Health Organization.Global recommendations on physical activity for health[M].Geneva:World Health Organization,2010:23-31.
[13] 王琛琛,周海茸,洪忻.南京市社区糖尿病患者血糖控制情况及自我管理水平分析[J].中华健康管理学杂志,2020,14(2):148-153.
[14] WANG S,WEN J,MIAO D,et al.Mediating effect of BMI on the relation of dietary patterns and glycemic control in T2DM patients:results from China community-based cross-sectional study[J].BMC Public Health,2023,23(1):468.
[15] 钟庆,李俊林,黄远霞,等.武汉市社区糖尿病患者血糖控制现状及影响因素分析[J].现代预防医学,2019,46(18):3355-3359,3368.
[16] JIA W,WENG J,ZHU D,et al.Standards of medical care for type 2 diabetes in China 2019[J].Diabetes Metab Res Rev,2019,35(6):e3158.
[17] LI Y,YU L,LIU Z,et al.Dietary pattern associated with the risk of poor glycemic control in Chinese diabetic adults:results from the china nutrition and health surveillance 2015-2017 survey[J].Nutrients,2022,15(1):56.
[18] WANG Q,ZHANG X,FANG L,et al.Prevalence,awareness,treatment and control of diabetes mellitus among middle-aged and elderly people in a rural Chinese population:a cross-sectional study[J].PLoS One,2018,13(6):e0198343.
[19] BRADY R,SHAH A,JENDEN E,et al.Glycemic control is associated with dyslipidemia over time in youth with type 2 diabetes:the SEARCH for diabetes in youth study[J].Pediatr Diabetes,2021,22(7):951-959.
[20] 付平,冯春红,杨超,血脂异常对2型糖尿病发生发展的影响[J].西南医科大学学报,2018,41(3):287-290.

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