Objective: To investigate the prevalence of osteoporosis(OP) and the related factors among the people in a hospital in Xi'an, and to provide reference for the prevention and treatment of OP. Methods: A total of4 618 people who underwent physical examination in the Physical Examination Department of the Second Affiliated Hospital of Xi'an Jiaotong University from January 2020 to December 2020 were enrolled in this study, excluding secondary OP and other factors affecting bone metabolism. They were divided into three groups according to bone mineral density(BMD), i.e., normal bone mass, decreased bone mass and OP groups. At the same time, they were subgrouped according to sex and menstrual status. The correlation between age, BMI, blood pressure, fasting blood glucose(FBG), blood lipids and BMD was analyzed. Results: The results showed that the overall prevalenceof osteoporosis in the study population was 17.65%. The age, body mass index(BMI), systolic blood pressure(SBP), diastolic blood pressure(DBP), FBG, and blood lipids of the OP group were higher than those of the normal and decreased bone mass groups, and there was no significant difference in triglycerides(TG)among the three groups. The prevalence of OP in the male population was 12.94%, and the age and SBP in the OP group were higher than those in the normal and decreased bone mass groups. There was no significant difference in FBG and blood lipid. The prevalence of OP in the female population was 23.40%. The age, BMI, SBP, DBP, FBG, total cholesterol(TC), TG, and low-density lipoprotein-cholesterol(LDL-C) in OP group were higher than those in the normal and decreased bone mass groups, and there was no significant difference in high-density lipoprotein cholesterol(HDL-C). The prevalence of OP in premenopausal women was 6.25%. The BMI, SBP and DBP of the OP group were higher than those of the normal and decreased bone mass groups. The prevalenceof OP in postmenopausal women was 43.23%. The age and SBP of the OP group were higher than those of the normal and decreased bone mass groups. Multivariate Logistic regression analysis showed that SBP was a risk factor for decreased BMD in men, premenopausal and postmenopausal women.Conclusion: The prevalence of OP in this study population is 17.65%, with 12.94% in males and 23.40% in females(6.25% in premenopausal women and 43.23% in postmenopausal women). BMD is related to BMI, FBG, blood pressure, blood lipids, etc. Different subgroups may have different susceptibility. |
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