新疆地区体检人群体质指数分布情况及其与血脂、血糖的相关性分析-现代医学

新疆地区体检人群体质指数分布情况及其与血脂、血糖的相关性分析

单位：1. 新疆医科大学第一附属医院临床医学研究院, 新疆乌鲁木齐 830054;
2. 新疆医科大学公共卫生学院, 新疆乌鲁木齐 830054;
3. 新疆医科大学第一附属医院临床检验中心, 新疆乌鲁木齐 830054;
4. 新疆医科大学医学工程技术学院, 新疆乌鲁木齐 830054

关键词：体质指数血脂血糖相关性回归分析

分类号：R194.3

出版年·卷·期（页码）：2022·50·第五期（555-561）

摘要：

目的：研究新疆地区体检人群体质指数（BMI）与血脂、血糖的相关性。方法：选择2011年7月至2013年6月在新疆医科大学第一附属医院、喀什第一人民医院、吐鲁番医院、托里县人民医院体检中心参加体检的10 097体检者为研究对象。测量身高、体重，计算BMI，采集空腹静脉血检测甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、空腹血糖（FPG）。多元数据采用多元统计分析，数据处理采用SPSS 22.0软件。结果：调查对象超重率和肥胖率分别为38.57％和32.43％，男女分布不同（χ²=87.293，P<0.001），男性超重率（P<0.05）和肥胖率（P<0.05）明显高于女性。不同年龄组人群BMI值分布不同（χ²=343.711，P<0.001）。男性30岁~组超重率最高（44.32%），50岁~组肥胖率最高（40.21%）；女性40岁~组超重率最高（39.18%），60岁~组肥胖率最高（38.04%）。不同BMI组人群血脂水平不同（Wilks'λ=0.957，F=56.678，P<0.001），BMI≥28组TG和LDL-C水平最高，HDL-C水平最低；BMI<24 kg·m^-2组TC水平低于BMI 24~28 kg·m^-2和≥28 kg·m^-2组；不同BMI组人群FPG分布不同（F=48.883，P<0.001）。BMI 24~28 kg·m^-2和≥28 kg·m^-2组人群FPG值均高于BMI<24组kg·m^-2（P<0.05）。女性的BMI与TC、TG和LDL-C呈正相关，与HDL-C均呈负相关（P<0.05）；男性BMI与TG、LDL-C和FPG均呈正相关，与HDL-C均呈负相关（P<0.05）。在校正年龄和性别后，超重组和肥胖组患血脂异常的风险分别是正常组的是1.667倍和1.951倍，患血糖异常的风险分别是正常组的是1.464倍和1.838倍，差异具有统计学意义（P<0.05）。结论：新疆地区体检人群超重肥胖率高，男性为高危人群，且BMI对血脂、血糖水平具有显著影响。

Objective:To study the correlation between the body mass index(BMI) and the blood lipid and fasting plasma glucose(FPG) in medical examination population in Xinjiang. Methods:The 10 097 subjects were selected from the physical examination center of the First Affiliated Hospital of Xinjiang Medical University, the First People's Hospital of Kashi, Turpan Hospital and the People's Hospital of Toli County from July 2011 to June 2013. The height and weight of the subjects were measured and their BMIs were calculated. Fasting venous blood was sampled to detect triglycerides(TG), total cholesterol(TC), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C) and FPG. Multivariate data were analyzed by multivariate statistical analysis. SPSS 22.0 software was used for statistical analysis. Results:The overweight rate and obesity rate of the surveyed subjects were 38.57% and 32.43%, respectively. And there was statistical difference between the male and the female(χ²=87.293, P<0.001). The overweight rate(P<0.05) and obesity rate(P<0.05) of the male were statistically higher than those of the female. The distribution of BMI in different age groups was statistically different(χ²=343.711, P<0.001). The men aged over 30 were more likely to be overweight(44.32%), and aged over 50 were more likely to be obese(40.21%). The women aged over 40 were more likely to be overweight(39.18%), and aged over 60 were more likely to be obese(38.04%). The blood lipid levels were different in different BMI groups(Wilks'λ=0.957, F=56.678, P<0.001). The levels of TG and LDL-C were the highest in the group with BMI ≥ 28 kg·m^-2. The level of TC was lower in the group with BMI<24 kg·m^-2 than BMI of 24-28 kg·m^-2 and BMI ≥ 28 kg·m^-2. The lowest HDL-C level was found in the group with BMI ≥ 28 kg·m^-2. The distribution of FPG varied in different BMI groups(F=48.883, P<0.001). The level of FPG was higher in BMI of 24-28 kg·m^-2 and BMI ≥ 28 kg·m^-2 than BMI<24 kg·m^-2 group(P<0.05). The BMI of females was positively correlated with TC, TG, LDL-C and FPG, but negatively correlated with HDL-C(P<0.05). The BMI of males was positively correlated with TG, LDL-C and FPG, but negatively correlated with HDL-C(P<0.05). After adjustment for age and gender, the risk of dyslipidemia was respectively 1.667 times higher in overweight group and 1.951 times higher in obesity group than those in the normal group, and the risk of pathoglycemia was respectively 1.464 times higher in overweight group and 1.838 times higher in obesity group than those in the normal group(P< 0.05). Conclusion:The prevalence of overweight and obesity among the medical examination population in Xinjiang is relatively high, of whom the male are higher risk group. BMI has a significant effect on blood lipid and glucose level in the population of Xinjiang.

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