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叶酸与肝癌关系的研究进展
作者:司薇1  徐丹2 
单位:1. 北华大学, 吉林 吉林 132013;
2. 北华大学附属医院, 吉林 吉林 132011
关键词:叶酸 肝细胞癌 肿瘤 综述 
分类号:R735.7
出版年·卷·期(页码):2022·50·第四期(509-512)
摘要:

肝细胞癌(HCC)起病隐匿,致死率高,有效提高HCC临床治疗效果对延长患者生存期尤为重要。叶酸(FA)是参与一碳单位的代谢及转移过程的甲基供体,是细胞内DNA合成所必需,如果体内FA缺乏,将造成机体生物代谢功能异常,进而增加肿瘤的发生发展风险。近年来,随着对FA与HCC相关性的研究,发现FA水平的变化可能与肝脏损伤以及HCC的发展密切相关。本文作者从FA的生物学特性、功能及对HCC发生发展的影响等方面进行综述,以期为HCC的临床治疗提供新方向。

参考文献:

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