Objective: To analyze the influencing factors of tumor recurrence in patients undergoing transhepatic arterial chemoembolization(TACE) after deletion of liver cancer surgery, and construct a nomogram prediction model, and then evaluate the model. Methods:A total of 215 liver cancer patients treated with TACE after radical resection in our hospital were selected to collect clinical and demographic characteristics such as gender and age, and followed up for 1 year, and divided into relapsed and unrelapsed groups according to whether the tumor relapsed.The influencing factors of univariateand multivariate logistic regression were analyzed for liver cancer recurrence after TACE and liver cancer, and a clinical predictive model based on influencing factors was constructed, and then evaluated by H-L fitting curve, receiver operating characteristic(ROC) curve and area under the curve(AUC). Finally, the predictive model was visualized as a nomogram. Results:In this study, the included patients were followed up for 1 year, and the results showed that 57 patients had tumor recurrence, accounting after TACE treatment of liver cancer(P<0.05), but it had no connection with age, liver cirrhosis, hepatitis B, surgical margin, intraoperative ascites, case classification, total hilar block time and Child-Pugh classification of liver function(P>0.05); the results of univariate analysis with significant differences were included in the multivariate logistic regression analysis, the results showed that vascular tumor thrombus, poor differentiation, and tumor diameter ≥5 cm were independent risk factors for recurrence after TACE treatment of liver cancer(P<0.05); based on the results of multivariate Logistic regression analysis, a nomogram prediction model for recurrence of liver cancer after TACE was constructed, and the model was evaluated with an H-L fit curve to evaluate its predictive effectiveness, the results showed that χ2=6.432, P=0.415. The area under the ROC curve was used to evaluate the discrimination of the model, the results showed that the area under the ROC curve was 0.880, the sensitivity was 87.7%, and the specificity was 85.4%.Conclusion: Vascular tumor thrombus, poor differentiation, and tumor diameter ≥5 cm are independent risk factors for tumor recurrence after postoperative TACE of liver cancer. The predictive model of nomogram constructed on this basis has good predictive value and distinguishability, and it can be used as an effective means of early clinical intervention. Vascular cancer embolus, low differentiation and tumor diameter of 5 cm are independent risk factors for tumor recurrence after postoperative TACE of liver cancer. The model constructed by this method has a good predictive value, differentiation and calibration, which can be used as an effective means for early clinical intervention. |