Objective:To improve the accuracy of early clinical diagnosis of malignant single lung nodules by constructing a predictive model for the diagnosis of benign and malignant single lung nodule.Methods:A retrospective summary of 112 patients who were admitted to our hospital from April 2017 to April 2020 and judged to be a single pulmonary nodule(nodule diameter 8 mm-3 cm), after 64-slice spiral CT enhanced scanning and reconstruction processing, confirmed by CT-guided needle biopsy or surgical pathology,confirmed including 40 cases of malignant nodules(malignant group) and 72 cases of benign nodules(benign group). Single factor analysis was used to compare the gender, age, nodule location, nodule diameter, internal and external texture features of the nodule, the internal features including lobes, cavities, calcification, blood supply, and external texture features including burrs, irregularities, bronchial signs and vascular bundles. Multi-factor Logistic regression analysis screened out the risk factors that affected the nature of judgment. manomogram prediction model showed that the greater the patient age and nodule diameter, the greater the number of nodule internal and external markings, the higher the likelihood of malignant nodules.The ROC analysis showed that the prediction accuracy of this model was 0.896, and the Hosmer-Lemeshow test was 91.07%, with good fit.Results:The age of the patients in malignant group was higher than that in benign group, and the number of internal and external texture features ofnodules increased(P<0.05), but there was no significant difference in gender, nodule location and nodular diameter between the two groups(P>0.05). Logistic regression analysis showed thatpatient's age,nodule diameter and the number of internal and external texture features ofnodules were independent risk factors that affecting the judgment of nature(P<0.05). Nomogram prediction model shows that the larger the patient's age andnodule diameter, the more the number of internal and external texture features of the nodule, suggesting the higher the probability ofmalignant nodule. ROC analysis shows that the prediction accuracy of the model is 0.896; the prediction efficiency of Hosmer-Lemeshow testis 91.07%, and the fitting effect is good.Conclusion:After 64-slice spiral CT enhanced scanning and reconstruction, a single small lung nodule has been processed to construct a predictive model for judging the nature of malignant nodules. The main indicators include patient age, nodule diameter, and the number of internal and external texture features of the nodule with good accuracy and application value. |