干骺续连症（HME）表现为多发外生骨疣和干骺端畸形，当病变在下肢引起下肢力线畸形时，需要通过手术矫正力线，减缓由于机械轴偏移引起的关节磨损和关节炎。膝外翻畸形可采用的手术方法有全膝关节置换术（TKA）和股骨远端截骨术（DFO），但是3D打印导板辅助双平面DFO治疗膝外翻畸形的研究较少。本文报道1例33岁患有HME合并重度骨质疏松和膝外翻畸形的女性患者，通过3D打印导板辅助双平面DFO手术矫正下肢畸形，取得了较好的术后效果。

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