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原癌基因MYC与多发性骨髓瘤关系的研究进展
作者:陈明翠1  郭鹏翔2 
单位:1. 贵州医科大学, 贵州 贵阳 550000;
2. 贵州医科大学附属人民医院 血液内科, 贵州 贵阳 550000
关键词:原癌基因MYC 多发性骨髓瘤 文献综述 
分类号:R733.3
出版年·卷·期(页码):2021·49·第五期(597-604)
摘要:

多发性骨髓瘤(MM)目前仍是一种不可治愈的恶性肿瘤,其发病机制尚不明确。在MM患者中常发现原癌基因MYC表达异常,原癌基因MYC及其编码的蛋白MYC在MM的发生、发展中发挥重要作用,MYC异常预示着疾病进展及预后不良,现已涌现出越来越多的靶向MYC的抗肿瘤药物。作者就原癌基因MYC表达与MM关系的研究进展作一综述。

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