Objective: To investigate the correlation between the distribution of intracranial arterial calcification and magnetic resonance imaging(MRI) findings of cerebral small vessel disease(CSVD).Methods: A total of 150 patients who visited our Hospitalbetween June 2017 and June 2019 and underwent CT and MRI examinations for lacunar infarction or white matter lesions were included in this study. The intracranial artery calcification was evaluated with the Agatston integral method. MRI was used to evaluate cerebral infarction, white matter hyperintensities(WMH), lacuna, cerebral microbleed(CMB), and intracerebral enlarged perivascular spaces(EPVS).Results: Intracranial artery calcification was found in 109 patients(72.67%), with the incidence of internal carotid artery(ICA) being the highest(64.7%). The severity of intracranial arterial calcification was correlated with WMH, lacuna, and CMB(r=0.348, r=0.284, r=0.250; P<0.05), but there was no correlation with EPVS(r=0.141; P=0.057). Adjusted odds ratios(OR) for intracranial arterial calcification were WMH(Grades 1-2)OR=2.745, WMH(Grade 3)OR=3.421, lacunaOR=2.901, CMB OR=2.448, EPVS(Grade 1) OR=0.870, and EPVS(Grades 2-4)OR=0.294.Conclusion: Intracranial artery calcification is common in patients with CSVD. Intracranial artery calcification is closely related to WMH,lacuna and CMB, all of which could be used as an important indices for predicting CSVD.
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