[1] TAKAHASHI T,HOLLAND P W,COHN M J,et al.An orphan PRD class homeobox gene expressed in mouse brain and limb development[J].Dev Genes Evol,2002,212(6):293-297.
[2] OHTOSHI A,BEHRINGER R R.Neonatal lethality,dwarfism,and abnormal brain development in Dmbx1 mutant mice[J].Mol Cell Biol,2004,24(17):7548-7558.
[3] WONG L,WEADICK C J,KUO C,et al.Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development[J].BMC Dev Biol,2010,10:100.
[4] RYAN J F,BURTON P M,MAZZA M E,et al.The cnidarian-bilaterian ancestor possessed at least 56 homeoboxes:evidence from the starlet sea anemone,Nematostella vectensis[J].Genome Biol,2006,7(7):R64.
[5] GALLIOT B,DE VARGAS C,MILLER D.Evolution of homeobox genes:Q50 paired-like genes founded the paired class[J].Dev Genes Evol,1999,209(3):186-197.
[6] HOLLAND P W,TAKAHASH T.The evolution of homeobox genes:implications for the study of brain development[J].Brain Res Bull,2005,66(4-6):484-490.
[7] SERRA-JUHE C,RODRIGUEZ-SANTIAGO B,CUSCO I,et al.Contribution of rare copy number variants to isolated human malformations[J].PLoS One,2012,7(10):e45530.
[8] KAWAHARA A,CHIEN C B,DAWID I B.The homeobox gene mbx is involved in eye and tectum development[J].Dev Biol,2002,248(1):107-117.
[9] BROCCOLI V,COLOMBO E,COSSU G.Dmbx1 is a paired-box containing gene specifically expressed in the caudal most brain structures[J].Mech Dev,2002,114(1-2):219-223.
[10] GOGOI R N,SCHUBERT F R,MARTINEZ-BARBERA J P,et al.The paired-type homeobox gene Dmbx1 marks the midbrain and pretectum[J].Mech Dev,2002,114(1-2):213-217.
[11] MIYAMOTO T,KAWAHAARA A,TEUFEL A,et al.Mbx,a novel mouse homeobox gene[J].Dev Genes Evol,2002,212(2):104-106.
[12] OHTOSHI A,NISHIJIMA I,JUSTICE M J,et al.Dmbx1,a novel evolutionarily conserved paired-like homeobox gene expressed in the brain of mouse embryos[J].Mech Dev,2002,110(1-2):241-244.
[13] ZHANG Y,MIKI T,IWANAGA T,et al.Identification,tissue expression,and functional characterization of Otx3,a novel member of the Otx family[J].J Biol Chem,2002,277(31):28065-28069.
[14] ACAMPORA D,GULISANO M,BROCCOLI V,et al.Otx genes in brain morphogenesis[J].Prog Neurobiol,2001,64(1):69-95.
[15] FURUKAWA T,MORROW E M,CEPKO C L.Crx,a novel otx-like homeobox gene,shows photoreceptor-specific expression and regulates photoreceptor differentiation[J].Cell,1997,91(4):531-541.
[16] FREUND C L,GREGORY-EVANS C Y,FURUKAWA T,et al.Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor[J].Cell,1997,91(4):543-553.
[17] FUJIMOTO W,SHIUCHI T,MIKI T,et al.Dmbx1 is essential in agouti-related protein action[J].Proc Natl Acad Sci U S A,2007,104(39):155140-155149.
[18] ALAZAMI A M,PATEL N,SHAMSELDIN H E,et al.Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families[J].Cell Rep,2015,10(2):148-161.
[19] HIRONO S,LEE E Y,KURIBAYASHI S,et al.Importance of adult dmbx1 in long-lasting orexigenic effect of agouti-related peptide[J].Endocrinology,2016,157(1):245-257.
[20] CHANG L,KHOO B,WONG L,et al.Genomic sequence and spatiotemporal expression comparison of zebrafish mbx1 and its paralog,mbx2[J].Dev Genes Evol,2006,216(10):647-654.
[21] ALFANO G,CONTE I,CARAMICO T,et al.Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye[J].Development,2011,138(2):261-271.
[22] BARABINO S M,SPADA F,COTELLI F,et al.Inactivation of the zebrafish homologue of Chx10 by antisense oligonucleotides causes eye malformations similar to the ocular retardation phenotype[J].Mech Dev,1997,63(2):133-143.
[23] STOLFI A,LEVINE M.Neuronal subtype specification in the spinal cord of a protovertebrate[J].Development,2011,138(5):995-1004.
[24] MILES A,TROPEPE V.Coordinating progenitor cell cycle exit and differentiation in the developing vertebrate retina[J].Neurogenesis (Austin),2016,3(1):e1161697.
[25] WONG L,POWER N,MILES A,et al.Mutual antagonism of the paired-type homeobox genes,vsx2 and dmbx1,regulates retinal progenitor cell cycle exit upstream of ccnd1 expression[J].Dev Biol,2015,402(2):216-228.
[26] AZZOLINI C,PAGANI I S,PIRRONE C,et al.Expression of VEGF-A,Otx homeobox and p53 family genes in proliferative vitreoretinopathy[J].Mediators Inflamm,2013,2013:857380.
[27] MIYAMOTO T,YU Y S,SATO H,et al.Mutational analysis of the human MBX gene in four Korean families demonstrating microphthalmia with congenital cataract[J].Turk J Pediatr,2007,49(3):334-336.
[28] ZHOU F,SHEN C,XU J,et al.Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis[J].Clin Epigenetics,2016,8:131.
[29] LUO J,LIU K,YAO Y,et al.DMBX1 promotes tumor proliferation and regulates cell cycle progression via repressing OTX2-mediated transcription of p21 in lung adenocarcinoma cell[J].Cancer Lett,2019,453:45-56.
[30] LARSEN K B,LUTTERODT M C,MOLLGARD K,et al.Expression of the homeobox genes OTX2 and OTX1 in theearly developing human brain[J].T J Histochem Cytochem,2010,58(7):669-678.
[31] MUOIO V M F,UNO M,OBA-SHINJO S,et al.OTX1 and OTX2 genes in medulloblastoma[J].World Neurosurg,2019,127:e58-e64.
[32] LU Y,LABAK C M,JAIN N,et al.OTX2 expression contributes to proliferation and progression in myc-amplified medulloblastoma[J].Am J Cancer Res,2017,7(3):647-656.
[33] BOULAY G,AWAD M E,RIGGI N,et al.OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma[J].Cancer Discov,2017,7(3):288-301.
[34] LI J,DI C,JING J,et al.OTX2 is a therapeutic target for retinoblastoma and may function as a common factor between C-MYC,CRX,and phosphorylated RB pathways[J].Int J Oncol,2015,47(5):1703-1710.
[35] KIMURA K,MIKI T,SHIBASAKI T,et al.Functional analysis of transcriptional repressor Otx3/Dmbx1[J].FEBS Lett,2005,579(13):2926-2932.
[36] ARAI T,KOJIMA S,YAMADA Y,et al.Pirin:a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p[J].Mol Oncol,2019,13(2):322-337.
[37] XU X,LIU T,WANG Y,et al.miRNA-mRNA associated with survival in endometrial cancer[J].Front Genet,2019,10:743. |
