Objective:To explore the effect of ICU clinical nurses specialist implementing early lung rehabilitation training in mechanical ventilation treatment of AECOPD patients.Methods: A total of 30 patients who were admitted to the ICU of our hospital from January to December 2018 under mechanical ventilation treatment were defined as a control group, receiving routine care; A total of 30 patients admitted to the ICU of our hospital from January to December 2019 and performed with AECOPD mechanical ventilation were as allocated into a experimental group, and ICU clinical specialist nurses underwent early lung rehabilitation training. The PaCO2 and oxygenation index were compared before and after intervention in the two groups. The incidence of related complications and the time of mechanical ventilation, ICU length of stay, cure rate and other outcome indicators were compared in the two groups of patients. Results:PaCO2 in the blood gas analysis was (41.05±1.00) in the experimental group after intervention, which was significantly lower than that of the control group after intervention (46.16±1.03), and the oxygenation index of the experimental group after intervention (191.10±7.29) was significantly higher after intervention, the oxygenation index (167.73±10.27) of the control group was statistically significant (P<0.05); the incidence of VAP, the incidence of reintubation at 24 hours, the incidence of delirium in ICU, the incidence of DVT in the lower limbs and the incidence of pressure ulcers was lower than that of the control group, for which the difference was statistically significant (P<0.05); the mechanical ventilation time and ICU stay time of the experimental group were lower than these of the control group, the difference was statistically significant (P<0.05); the cure and improvement rate were counted as 80% in the experimental group, which was higher than the control group by 53.3%, with a statistically significant difference (P<0.05). Conclusion: The implementation of early lung rehabilitation training by ICU clinical nurse specialists can reduce the rate of ventilator-associated pneumonia, the incidence of reintubation, the incidence of ICU delirium, the incidence of lower limb DVT and the incidence of pressure ulcers, as well as it can also shorten ICU stay time and time of mechanical ventilation, which can improve the cure rate of patient and have better results in improving clinical outcomes.
 CORDOBA-LANUS E,CAZORLA-RIVERO S,EAPINOZA-JIMENEZ A,et al.Telomere shortortening and accelerated aging in COPD:Findings from the BODE cohort[J].Respir Res,2017,18(1):59.
 PIZZINI A,FILIPIAK W,WILLE J,et al.Analysis of volatile organic compounds in the breath of patients with stable or acute exacerbation of chronic obstructive pulmonary disease[J].J Breath Res,2018,12(3):036002.
 SPRUIT M A,SINGH S J,GARVEY C,et al.An official American thoracic society/European respiratory society statement:key concepts and advances in pulmonary rehabilitation[J].Am J Respir Crit Care Med,2013,188(8):e13-e64.
 ZOUMOT Z,JORDAN S,HOPKINSON N S.Emphysema:time to say farewell to therapeutic nihilism[J].Thorax,2014,69(11):973-975.
 ROCHESTER C L,VOGIATZIS I,HOLLAND A E,et al.An official American thoracic society/European respiratory society policy statement:enhancing implementation,use,and delivery of pulmonary rehabilitation[J].Am J Respir Crit Care Med,2015,192(11):1373-1386.
 LIANG G P,LIU T T,ZENG Y H,et al.Characteristics of subjects who failed a 120-minute spontaneous breathing trial[J].Respir Care,2018,63(4):388-394.
 KOKTURK N,GURGUN A,SEN E,et al.The view of the turkish thoracic society on the report of the GOLD 2017 global strategy for the diagnosis,management,and prevention of COPD[J].Turk Thorac J,2017,18(2):57-64.
 HASSAN Z M,WAHSHEH M A.Knowledge level of nurses in Jordan on ventilator-associated pneumonia and preventive measures[J].Nurs Crit Care,2017,22(3):125-132.
 WRIGHT S E,THOMAS K,WATSON G,et al.Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC):A multicentre,parallel-group,randomised controlled trial[J].Thorax,2018,73(3):213-221.
 MAGALHAES P A F,CAMILLO C A,LANGER D,et al.Weaning failure and respiratory muscle function:what has been done and what can be improved?[J].Respir Mde,2018,134:54-61.