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丹参多酚酸盐对冠心病心绞痛患者超声心动图、相关血清指标及SAQ评分的影响
作者:韩倩  崔维佳 
单位:成都市西区医院 心内科, 四川 成都 610000
关键词:丹参多酚酸盐 冠心病心绞痛 超声心动图 血清指标 
分类号:R541.4
出版年·卷·期(页码):2020·48·第十期(1284-1287)
摘要:

目的:探讨丹参多酚酸盐对冠心病心绞痛患者超声心动图、相关血清指标及西雅图心绞痛量表(SAQ)评分的影响。方法:选取我科收治的90例冠心病心绞痛患者,根据药物治疗方式的不同,将其分为研究组及对照组,各45例。对照组患者均接受常规治疗,治疗组在对照组的基础上加用丹参多酚酸盐治疗,比较两组患者的临床疗效。结果:治疗后研究组患者临床总有效率(91.1%)显著高于对照组患者(68.9%)(P<0.05);两组患者治疗前后的超声心动图相关指标、相关血清指标及SAQ评分差值比较,差异有统计学意义(P<0.05)。结论:常规治疗辅以丹参多酚酸盐治疗冠心病心绞痛更具优势,能够显著改善患者的心功能,降低其氧化应激程度并提高生活质量,值得临床实践中推广应用。

Objective: To investigate the effect of salvianolate on echocardiography, related serum indexes and Seattle Angina Questionnaire(SAQ) score in patients with angina pectoris. Methods: 90 patients with angina pectoris weredivided into study group and control group,each group included 45 cases. The control group received conventional treatment, while the treatment group was treated with salvianolate on the basis of the control group.The clinical efficacy of the two groups was compared.Results: After treatment, the clinical total effective rate of the study group(91.1%) was significantly higher than that of the control group(68.9%)(P<0.05); The difference of echocardiography related indexs, related serum indexes and SAQ scores between the two groups before and after treatment were statistically significant(P < 0.05). Conclusion: The conventional treatment combined with salvianolate has more advantages in the treatment of angina pectoris, which can significantly improve the cardiac function of patients, reduce the degree of oxidative stress and improve the quality of life.It was worthy of clinical application.

参考文献:

[1] 张慧,朱艳,周岩芬.稳定型心绞痛患者血浆甘氨酸水平与急性心肌梗死风险关系的研究[J].现代医学,2017,45(1):43-47.
[2] FUKUOKA S,OKAMOTO R,TANIGAWA T,et al.Tracking angina pectoris on the coronary fractional flow reserve[J].Intern Med,2016,55(16):2311-2312.
[3] LI H Y,ZHAO X,LIU Y Z,et al.Plasma microRNA-126-5p is associated with the complexity and severity of coronary artery disease in patients with stable angina pectoris[J].Cell Physiol Biochem,2016,39(3):837-846.
[4] 刘倩,郭更新,刘爱翔,等.丹参多酚酸盐对原发性肾病综合征患者血液高凝状态影响[J].临床军医杂志,2017,45(9):918-921,925.
[5] 邱晗,潘玲.益心胶囊与参松养心胶囊治疗冠心病心绞痛的临床疗效比较[J].重庆医学,2015,44(33):4709-4711.
[6] 颜红兵,霍勇.《2019年欧洲心脏病学会慢性冠状动脉综合征诊断和管理指南》——冠状动脉疾病治疗:从归类走向精准[J].中国介入心脏病学杂志,2019,170(9):7-9.
[7] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:68-72.
[8] SPERTUS J A,WINDER J A,DEWHURST T A,et al.Monitoring the quality of life in patients with coronary artery disease[J].Am J Cardiol,1994,74(12):1240-1244.
[9] 张婷婷,李鹏,徐昉,等.丹桂三香汤对冠心病心绞痛患者氧化应激反应的影响[J].中华中医药杂志,2015,30(11):4180-4183.
[10] 刘玉衡,金立军.冠心病患者药物治疗依从性的研究进展[J].心血管病学进展,2019,40(1):119-122.
[11] 郑效坤.冠心病心绞痛的研究现状[J].中国伤残医学,2015,23(8):206-207.
[12] 龚昌杰,周亮,杨德钱.中医及中西医结合治疗冠心病心绞痛研究进展[J].实用中医药杂志,2015,31(9):875-877.
[13] 朱振宇,李永东.丹参多酚酸盐对冠心病的作用机制与临床效果[J].医学综述,2017,23(5):948-952.
[14] 储莉.不同剂量阿托伐他汀对不稳定性心绞痛介入治疗术后患者的影响[J].安徽医学,2014,35(7):959-962.
[15] 周保祥.丹参多酚酸盐治疗冠心病心绞痛(心血瘀阻)临床疗效及对血液流变学影响[J].中国中医基础医学杂志,2014,20(10):1388-1390.

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