Objective: To explore the differences in efficacy and health economics of two different warming intervention in patients undergoing colorectal cancer surgery.Methods: 200 patients who planned for colorectal tumor surgery from September to December in 2019 were selected and divided into experimental group(Group B) and control group(Group A) according to the random number table method, 100 patients in the experimental group and 100 patients in the control group. Each group was divided into two subgroups according to the different operating methods, patients with laparotomy were recruited in Group A1or B1, while those with laparoscopic surgery in Group A2 or B2, 50 in each subgroup. The test group was kept warm with forced-air warming blankets when the patients came into the operating room, and the control group was given warming measures after anesthesia.Results: The incidence of hypothermia and complications in group B was lower than that of group A (P<0.05). The total hospitalization expenses in group A2 was higher compared to group B2 (P<0.05),while higher than that of group A1 (P<0.05). The average length of hospital stay in group B1 was shorter than that in group A1, and the average length of hospital stay ingroup B2 was significantly shorter compared to group A1/A2/B1. Conclusion: The pre-warming treatment can effectively reduce postoperative hypothermia and complications in patients underwent colorectal tumor surgery, and shorten the length of hospital stay with health economic significance.