右旋糖酐铁联合五维赖氨酸治疗婴儿营养性缺铁性贫血的综合疗效-现代医学

右旋糖酐铁联合五维赖氨酸治疗婴儿营养性缺铁性贫血的综合疗效

单位：1. 聊城市东昌府区妇幼保健院儿保科, 山东聊城 252000;
2. 聊城市第三人民医院骨科, 山东聊城 252000

分类号：R556.3

出版年·卷·期（页码）：2020·39·第八期（1020-1024）

摘要：

目的：研究右旋糖酐铁联合五维赖氨酸颗粒对婴儿营养性缺铁性贫血的血红蛋白水平以及发育商的影响。方法：124例门诊患儿随机分为研究组（63例）和对照组（61例），对照组给予右旋糖酐铁口服液配合口服维生素C片辅助治疗，研究组在此基础上加用五维赖氨酸颗粒，统一治疗8周。比较两组间血红蛋白水平和发育商数值的变化。结果：研究组患儿Hb增长幅度明显大于对照组（P<0.01）；研究组的DQ数值增幅明显高于对照组（P<0.01）；研究组的总有效率（95.24%）大于对照组的总有效率（81.97%），P<0.05；研究组的不良反应率（4.76%）小于对照组的不良反应率（16.39%），P<0.05。结论：与单用铁剂相比较，右旋糖酐铁联合五维赖氨酸颗粒治疗婴儿营养性缺铁性贫血，能较快提升血红蛋白水平以及发育商数值，可进一步提高疗效。

Objective: To investigate the effects of iron dextran and five-dimensional lysine granules on hemoglobin levels and developmental quotients in infants with nutritional iron deficiency anemia.Methods: 124 outpatients were randomly divided into study group (63 cases) and control group (61 cases). The control group was given iron dextran oral solution combined with oral vitamin C tablets for adjuvant treatment, on top of which, the study groupwas given five-dimensional lysine granules for 8 weeks. The changes in hemoglobin levels and developmental quotient values were compared between the two groups.Results: The growth rate of Hb in the study group was significantly higher than that in the control group (P<0.01). The DQ value of the study group was significantly higher than that of the control group (P<0.01).The total effective rate of the study group (95.24%) was greater than the total effective rate of the control group (81.97%), P<0.05. The adverse reaction rate of the study group (4.76%) was lower than that of the control group (16.39%), P<0.05.Conclusion: Compared with iron alone, iron dextran combined with five-dimensional lysine granules can improve hemoglobin levels and developmental quotient values in infants with nutritional iron deficiency anemia. At the same time, this method can further improve the curative effect.

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