随着对维生素D的免疫调节作用和系统性红斑狼疮（SLE）发病机制研究的不断深入，我们认识到SLE患者普遍存在的低血清维生素D水平不仅是疾病发展的结果，更有可能是疾病发生和发展过程中一个重要因素；此外维生素D在SLE多器官和系统中的骨骼外作用及作用机制也受到了越来越多的关注，包括肾脏、神经系统、心血管系统等，为SLE患者补充维生素D制剂提供了更多的证据，但SLE患者最适宜的血清维生素D水平还需更多的研究支持。作者就维生素D与SLE相关性的研究进展予以综述。

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