目的：观察不同衰弱评分老年住院患者肌肉减少症的严重程度，并分析两者的相关性。方法：选取老年肌肉减少症患者119例，采用中文版基于照护者的老年综合评估的衰弱指数（CP-FI-CGA）问卷评价衰弱程度，并根据结果分为轻度衰弱（<0.3分）组44例、中度衰弱（0.3~0.5分）组35例及重度衰弱（>0.5分）组40例，比较各组去脂体重、四肢骨骼肌质量（ASM）、相对骨骼肌质量（RASM）、握力及6 m步行时间。采用Spearman相关分析衰弱程度与肌肉减少症严重程度的相关性。结果：随衰弱程度的加重，各组去脂体重、ASM、RASM及握力均逐渐降低，6 m步行时间逐渐增加，差异有统计学意义（P<0.05）。重度衰弱组去脂体重、ASM、RASM及握力均低于中度衰弱组和轻度衰弱组，6 m步行时间多于轻度衰弱组（P<0.05）；中度衰弱组ASM、RASM、握力低于轻度衰弱组，6 m步行时间多于轻度衰弱组（P<0.05）。Spearman相关分析显示，衰弱程度与ASM、RASM及握力呈负相关（r=-0.656、-0.672、-0.583，均P<0.001），与去脂体重、6 m步行时间无相关性（r=-0.214、0.114，P=0.095、0.120）。结论：随衰弱程度的增加，老年患者肌肉减少症的严重程度逐渐升高。

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