磁共振多模态成像在不同级别胶质瘤术后残留中的应用研究-现代医学

磁共振多模态成像在不同级别胶质瘤术后残留中的应用研究

单位：1. 南京市第二医院介入科, 江苏南京 210008;
2. 江苏省肿瘤医院 CT与MRI室, 江苏南京 210009;
3. 江苏省肿瘤医院放疗科, 江苏南京 210009

关键词：磁共振多模态成像灌注加权成像扩散加权成像氢质子波谱成像扩散张量成像神经胶质瘤分级残留

分类号：R739.4;R445.2

出版年·卷·期（页码）：2020·39·第五期（584-588）

摘要：

目的：探讨磁共振多模态成像在显示残留灶范围及在胶质瘤分级中的应用。方法：回顾性分析17例高级别胶质瘤术后残留及13例低级别胶质瘤术后残留患者的灌注加权成像（PWI）、弥散加权成像（DWI）、弥散张量成像（DTI）及氢质子波谱成像（¹H-MRS）的影像和临床资料。结果：高级别胶质瘤相对脑血容量（rCBV）为2.73±0.27、相对ADC值（rADC）为0.83±0.08，与低级别胶质瘤的1.55±0.34、1.62±0.14比较，差异有统计学意义（P<0.01）。高级别胶质瘤与低级别胶质瘤的相对部分各向异性（rFA）值分别为0.91±0.05和0.91±0.04，Cho/NAA值分别为9.73±10.68和7.11±3.64，差异无统计学意义（P>0.05）。结论：多模态磁共振成像在脑胶质瘤级别判定方面具有较大的诊断价值，可以更加全面完整地显示残留灶的范围。

Objective: To investigate the application of magnetic resonance multi modality imaging in grading and showing residue glioma comprehensive.Methods: Retrospectively analyzed the imaging including perfusion weighted imaging (PWI), diffusion weighted imaging (DWI), ¹H-magnetic resonance spectroscopic imaging(¹H-MRS) and diffusion tensor imaging (DTI), and clinical data of 17 cases with high grade glioma and 13 cases with low grade glioma all were post-operation.Results: The average relative-cerebral blood volume (rCBV) of high and low grade glioma were 2.73±0.27 and 1.55±0.34, the relative-apparent diffusion coefficient (rADC) value of high and low grade glioma were 0.83±0.08 and 1.62±0.14 respectively, there were statistical difference between them(P<0.01). The Cho/NAA and relative-fractional anisotropy (rFA) value were 9.73±10.68 and 7.11±3.64, 0.91±0.05 and 0.91±0.04 respectively, which showed no significant difference(P>0.05). All the parameters of MRI between tumor and peritumoral area had statistical difference.Conclusion: Magnetic resonance multi modality imaging is valuable in grading glioma, and can comprehensively show the range of residue glioma.

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