近视周边视网膜变性与眼生物测量值及优势眼的相关性研究-现代医学

近视周边视网膜变性与眼生物测量值及优势眼的相关性研究

单位：宁波市海曙区第二医院眼科, 浙江宁波 315040

分类号：R774.1

出版年·卷·期（页码）：2020·39·第四期（521-525）

摘要：

目的：研究注视性优势眼及眼生物测量值与近视眼周边视网膜变性发生的相关性。方法：回顾性选取2016年3月1日至2017年8月13日在宁波市鄞州人民医院眼科中心行近视激光手术的患者，筛检其术前检查的数据，收录近视眼周边视网膜变性的病例93例（135眼），其中单眼周边视网膜变性51例，双眼周边视网膜变性42例，男44例，女49例。将单眼周边视网膜变性的对侧健康眼设为对照（51眼），分别收集记录这186眼者的年龄、平时戴镜视力，有效矫正眼压、主觉等效球镜值、散瞳后等效球镜值、晶状体调节屈光度（主觉性-散瞳后）、中央角膜厚度、中央前房深度、眼轴长度。其中单眼周边视网膜变性患者，通过卡洞法检测注视性优势眼。分析以上数据相关性。结果：周边视网膜变性眼的晶状体调节屈光度均值大于健康眼，差异具有统计学意义（t=2.472，P=0.014）；主觉等效球镜均值大于健康眼，差异具有统计学意义（t=2.308，P=0.002）。注视性优势眼与周边视网膜变性呈现负相关（t=-4.13，P<0.001）。主觉等效球镜和眼轴长度在单眼周边视网膜变性的病例中存在相关性（t=27.976，P<0.05）。年龄（P>0.05）、性别（χ²=0.767，P=0.38）、最佳矫正视力（P>0.05）、有效矫正眼压（P>0.05）、中央角膜厚度（t=0.982，P=0.327）、中央前房深度（t=1.02，P=3.08）、眼轴长度（t=1.552，P=0.222）与周边视网膜变性不呈现相关性。结论：晶状体调节力的加强及是否为注视性优势眼与近视眼发生周边视网膜变性具有相关性，可为近视眼周边视网膜变性的预防和早期筛检提供参考。

Objective: To study the correlation betweendominant eye,ocular biometric measurements and peripheral retinal degeneration of myopia. Methods: Ninety-three patients(135 eyes) with myopia peripheral retinal degeneration and 51 healthy control subjects were selectedfrom Marth 1,2016 and August 13,2017. 44 males,49 females,42 in both eyes,51 in monocular. The age, BCVA, effective corrective NCT, primary esthetic equivalent spherical mirror value, the pupil equivalent spherical mirror value, the lens adjusts the diopter number(primary esthetic-after pupil), CCT, ACD and AL were collected and analyzed. Using hole-in-card method to detect the dominate eye to analyze the correlation in the patients of peripheral retinal degeneration was found in monocular.Results: Mean value of lens regulation in peripheral retinopathy eyes is greater than healthy eyes,The difference was statistically significant(t=2.472,P=0.014),mean value of primary esthetic equivalent spherical mirror is greater than healthy eyes, the difference was statistically significant(t=2.308,P=0.002).The dominate eye and peripheral retinal degeneration are negatively correlated, The difference was statistically significant(t=-4.13,P<0.001). Primary esthetic equivalent spherical mirror and AL in case of peripheral retinal degeneration of one eye are present correlation,The difference was statistically significant(t=27.976,P<0.05).Age(P>0.05), sex(χ²=0.767,P=0.38), BCVA(P>0.05), effective corrective NCT(P>0.05), CCT(t=0.982,P=0.327), ACD(t=1.02,P=3.08), AL(t=1.552,P=0.222)had no correlation withperipheral retinal degeneration.Conclusion: There is a correlation between Myopia peripheral retinal degeneration and the enhancement of lens regulation and dominant eye. The prevention and early screening of peripheral retinal degeneration in myopia can provide reference.

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