CO<sub>2</sub>激光治疗皮肤鳞状细胞癌的疗效观察-现代医学

CO₂激光治疗皮肤鳞状细胞癌的疗效观察

单位：四川大学华西医院皮肤科, 四川成都 610041

分类号：R739.5

出版年·卷·期（页码）：2020·39·第四期（505-507）

摘要：

目的：探究CO₂激光治疗对皮肤鳞状细胞癌的疗效。方法：以我院皮肤科2016年8月至2017年7月收治的90例皮肤鳞状细胞癌患者作为研究对象，随机分为对照组与观察组，每组45例。对照组患者根据病情给予常规治疗，包括手术治疗、药物控制等；观察组患者在常规治疗的基础上给予CO₂激光治疗。比较两组患者皮肤鳞状细胞癌总缓解率、皮损消失时间、皮损缩小50%时间、皮肤坏死率及复发率等。结果：观察组患者皮肤鳞状细胞癌的缓解率显著高于对照组患者，且皮损消失时间、皮损缩小50%时间显著短于对照组，皮肤坏死率及复发率优于对照组，差异均具有统计学意义（均P<0.05）。结论：CO₂激光治疗能够显著抑制皮肤鳞状细胞癌的复发，降低皮损部位的坏死率，提高总体有效程度，可作为皮肤鳞状细胞癌的有效治疗手段。

Objective: To explore the effects of CO₂ laser treatment on skin squamous cell carcinoma. Methods: 90 patients with squamous cell carcinoma of the dermatology admitted to our department of dermatology from August 2016 to July 2017 were randomly divided into control group and observation group, with 45 patients in each group. Control group receivedconventional treatment, including surgery, drug control, while observation group received CO₂ laser treatment on the basis of conventional treatment. Two groups were compared with total remission rate,lesions disappeared time and the time of 50% lesion reduction, along with skin necrosis rate and recurrence rate. Results: The total remission rate of skin squamous cell carcinoma in the observation group was significantly higher than that in the control group, andthe disappearance time and 50% reduction time of skin lesions were significantly less than those in the control group, moreover the skin necrosis rate and recurrence rate were better than those in the control group(P<0.05). Conclusion: CO₂ laser treatment can significantly inhibit the recurrence of skin squamous cell carcinoma, reduce the necrosis rate of skin lesions, and improve the overall effectiveness, suggesting that CO₂ laser treatment can be used as a treatment for skin squamous cell carcinoma and improve the overall effect of clinical treatment.

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