儿童难治性肺炎支原体肺炎临床分析-现代医学

儿童难治性肺炎支原体肺炎临床分析

单位：1. 南宁市第一人民医院儿科, 广西南宁 530022;
2. 广西壮族自治区妇幼保健院急诊内科, 广西南宁 530000;
3. 广西医科大学第一附属医院儿科, 广西南宁 530021

分类号：R725

出版年·卷·期（页码）：2020·48·第二期（235-239）

摘要：

目的： 探讨儿童难治性肺炎支原体肺炎（RMPP）的临床特点及治疗经验。方法： 分别选取我院2015年6月至2017年6月住院的RMPP患儿及普通肺炎支原体肺炎患儿各43例为研究对象，分为RMPP组及普通组，对其临床资料进行回顾性统计分析。两组患儿均接受阿奇霉素静脉输液治疗（其中RMPP组连用7~10 d，对照组连用5~7 d），后改为口服3 d停4 d，总疗程2~3周。RMPP组患儿在上述治疗的基础，同时给予甲泼尼龙进行治疗。结果： 1.治疗前RMPP患儿血清ESR、CRP、IL-6的水平高于普通组P<0.05。2.治疗后RMPP组患儿ESR、CRP、IL-6均较治疗前明显改善（P<0.05）。结论： 阿奇霉素联合甲泼尼龙能改善RMPP患儿临床症状、炎症水平以及影像学表现。

Objective: To explore the clinical features and therapeutic experience of children refractory mycoplasma pneumoniae (RMPP). Methods: 43 patients of refractory mycoplasma pneumoniae pneumonia children as RMPP group and 43 normal children with pneumonia mycoplasma pneumonia as general group from June 2015 to June 2017 in the hospital were retrospectivel analyzed. Both groups were treated with azithromycin intravenous infusion (RMPP group for 7~10 days, general group for 5~7 days), followed by 3 days of 4 days of oral administration lasting 2 to 3 weeks as a complete treatment on top of which the children in the RMPP group were treated with methylprednisolone. Results: 1. The serum levels of ESR, CRP and IL-6 in children with RMPP before treatment were higher than those in normal group P<0.05. 2. After treatment, the levels of ESR, CRP and IL-6 in children with RMPP were significantly improved (P<0.05). Conclusion: Azithromycin combined with methylprednisolone can improve clinical symptoms, inflammation and imaging findings in children with RMPP.

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