平逆方联合抗酸治疗肝胃郁热型咽喉反流病的疗效研究-现代医学

平逆方联合抗酸治疗肝胃郁热型咽喉反流病的疗效研究

作者：邢艳莉¹ 曹海滨² 鲍红琴¹ 吴昆仑³ 都乐亦³ 卢向莉⁴ 叶璐³ 翟健钧¹ 胥伟华¹

单位：1. 海军医科大学附属公利医院耳鼻喉科上海 200135;
2. 海军医科大学附属公利医院消化内科上海 200135;
3. 海军医科大学附属公利医院中医科上海 200135;
4. 新疆莎车县人民医院耳鼻喉科新疆喀什 844700

分类号：R259

出版年·卷·期（页码）：2020·48·第二期（226-230）

摘要：

目的： 分析平逆方联合抗酸治疗肝胃郁热型咽喉反流病（LPRD）的疗效。方法： 抽取100例2016年1月~2017年12月期间诊断为肝胃郁热型LPRD的患者，根据治疗方式结合患者意愿将患者分为"平逆方"+抗酸治疗组为A组（n=42）、"平逆方"组为B组（n=38）、抗酸组为C组（n=20），比较治疗2个月后反流症状指数量表（RSI）和反流体征指数量表（RFS）量表评分、回流总数、总回流时间。结果： 治疗后，三组患者平均RSI低于13分，RFS低于7分，A组RFS、RSI评分总分均显著低于B组、C组（P<0.05），A组在喉室消失、杓会厌襞红斑/充血、嘶声或发声障碍、持续清嗓子、烧心胸痛胃酸反流方面明显优于B、C组（P<0.05），B、C组组间比较无显著性差异（P>0.05）。治疗前，三组回流总数、总回流时间比较无明显差异（P>0.05），治疗后，三组回流总数、总回流时间均改善显著（P<0.05），A组优于B、C两组（P<0.05）。结论： 中西医联合治疗比单一治疗可以更好改善LPRD症状。

Objective: To analyze the efficacy of Pingni decoction combined with anti-acid therapy in treating Liver Stomach Heat Accumulation Syndrome of laryngopharyngeal reflux disease (LPRD). Methods: A total of 100 patients with a diagnosis of liver-disease-pyresteric LPRD between January 2016 to December 2017 were selected. Patients were divided into group A (n=42),group B (n=38)and group C (n=20),according to the patient's wishes combined with the treatment method. Group A was treated with "ping reversal formula" and antacid treatment; group B was given "ping reversal" group; group C was given anti-acid group. Reflux symptom index (RSI), reflux finding score (RFS) total number of reflux, and total reflux time were compared after 2 months of treatment. Results: After treatment, the RSI was lower than 13 and the RFS was lower than 7 in all three groups. The total scores of RFS and RSI in group A were significantly lower than those in group B and C (P<0.05).Group A disappeared in the larynx, epiglottis edema, erythema/congestion, snoring or vocal disturbances, sustained clearing of the throat, heartburn chest pain acid reflux was significantly better compared with the group B and C (P<0.05), while there was no significant difference between B and C group (P>0.05).Before treatment, there was no significant difference of case number of reflux and total reflux time between the three groups (P>0.05). After treatment, the total case number of reflux and the total reflux time of the three groups improved significantly (P<0.05). Group A was superior to group B and C (P<0.05).Conclusion: Combination of Chinese and Western medicine can better improve the symptoms of LPRD than single treatment.

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