网站首页期刊介绍通知公告编 委 会投稿须知电子期刊广告合作联系我们
最新消息:
前后路减压融合术治疗颈椎后纵韧带骨化症的效果
作者:王贵江  申沧海  崔涛  杨健  孙立山  彭宁宁  杨成  王力国 
单位:沧州市中心医院 骨四科, 河北 沧州 061001
关键词:脊椎后纵韧带 骨化症 前入路减压 后入路减压 
分类号:R681.5+5
出版年·卷·期(页码):2020·48·第二期(188-194)
摘要:

目的: 探究前后路减压融合术治疗复杂颈椎后纵韧带骨化的临床效果。方法: 选取2015年3月至2017年5月间在我院诊断并治疗的颈椎后纵韧带骨化症的患者86例,以手术入路方式不同分为前路减压融合术(ADF)组及后路减压融合术(PDF)组,每组43例,统计并对比两组手术时长、术中出血及住院时间;对比患者治疗前后疼痛程度(视觉模拟评分,VAS)及治疗前后颈椎功能(日本骨科学会评分,JOA);记录比较各组治疗相关并发症发生情况,同时对比治疗前后脊髓压迫情况,包括:椎管狭窄率、椎管面积及脊髓/椎管比。结果: ADF组的手术时长显著高于PDF组(t=2.641,P=0.010),ADF组的术中出血量显著小于PDF组(t=-37.961,P=0.000);术后两组VAS评分均显著下降(P<0.05),其中ADF组在术后15 d及术后30 d的VAS评分显著小于PDF组(t=-2.853,-9.693;P=0.005,0.000);两组患者治疗后30 d和1年的JOA评分均较术前均显著提高(P<0.05),ADF组的脊柱后凸患者改善率显著高于PDF组(t=2.175;P=0.032);ADF组的治疗相关并发症发生率显著高于PDF组(37.21% vs 9.30%;χ2=6.279,P=0.012);术后1年两组的椎管狭窄率及脊髓/椎管比较治疗前显著下降(P<0.05),椎管面积较治疗前显著提高(P<0.05),两组上述指标治疗前后差值无明显差异(P>0.05)。结论: 前入路减压及后入路减压均具有较好的治疗颈椎后纵韧带骨化症的疗效,前入路方式在术中出血、疼痛改善及脊柱后凸的治疗方面具有优势,后入路方式在手术时长、治疗并发症方面具有优势,两者远期治疗情况相似。

Objective: To explore the effect of anterior and posterior decompression fusion in treatment of OPLL. Methods: 84 patients with ossification of posterior longitudinal ligament in our hospital from March 2015 to May 2017 were divided into ADF group (43 cases) and PDF group (43 cases) according to the operation. The operative time, intraoperative bleeding and hospital stays of each group were compared, the VAS score and JOA score before and after treatment were compared, the incidence of therapeutic complications and compression including spinal stenosis rate, canal area and spinal cord-to-spinal canal ratio were also compared. Results: The operative longer time(t=2.641,P=0. 010)and less intraoperative bleeding(t=-37.961,P=0.000) in the ADF were observed compared with the PDF group. Both VAS score were significantly reduced after treatment(P<0.05), the score of the ADF group on postoperative d 15 and d 30 was significantly lower than that of the PDF(t=-2.853,-9.693;P=0.005,0.000), Both JOA scores were significantly increased after treatment(P<0.05),the improvement rate of kyphotic patients in the ADF group was significantly higher than that of the PDF group(t=2.175;P=0.032), the incidence of treatment-related complications in the ADF group was significantly higher than that of the PDF group(37.21% vs 9.30%; χ2=6.279,P=0.012). The spinal stenosis rate and spinal cord-to-spinal canal ratio of both groups in postoperative 1 year were significantly decreased while the canal area were significantly increased(P<0.05), there was no significant difference on the above indicators between the two groups before and after treatment(P>0.05). Conclusions: Both ADF and PDF have equal good effect on the treatment of OPLL, ADF has advantages in less intraoperative bleeding volume, better pain improvement and kyphosis treatment, while PDF has advantages in operation time and treatment complications, the long-term effects of the two groups are similar.

参考文献:

[1] WU D,LIU C Z,YANG H,et al.Surgical interventions for cervical spondylosis due to ossification of posterior longitudinal ligament:A meta-analysis[J].Medicine (Baltimore),2017,96(33):e7590.
[2] 李鹏飞.后纵韧带骨化症研究进展[J].内蒙古医学杂志,2013,45(2):193-195.
[3] HIRAI T,YOSHII T,IWANAMI A,et al.Prevalence and distribution of ossified lesions in the whole spine of patients with cervical ossification of the posterior longitudinal ligament a multicenter study (JOSL CT study)[J].PLoS One,2016,11(8):e0160117.
[4] YANG B,WANG Y,HE X,Li H.Treatment for thoracic ossification of posterior longitudinal ligament with posterior circumferential decompression:complications and managements[J].J Orthop Surg Res,2016,11(1):153.
[5] 汪文龙,海涌,关立,等.前路或后路手术治疗颈椎后纵韧带骨化症的中期疗效观察[J].中国脊柱脊髓杂志,2016,26(7):577-584.
[6] ABIOLA R,RUBERY P,MESFIN A.Ossification of the posterior longitudinal ligament:Etiology,diagnosis,and outcomes of nonoperative and operative management[J].Global Spine J,2016,6(2):195-204.
[7] SUN M,KONG L,JIANG Z,et al.Microscope enhanced the efficacy and safety of anterior cervical surgery for managing cervical ossification of the posterior longitudinal ligament[J].Med Sci Monit,2017,23:3088-3094.
[8] KIM C H,RENALDO N,CHUNG C K,et al.Use of an ultrasonic osteotome for direct removal of beak-type ossification of posterior longitudinal ligament in the thoracic spine[J].J Korean Neurosurg Soc,2015,58(6):571-577.
[9] LI H,ZHOU X,CHEN G,et al.Radiological manifestations and surgical outcome of combined upper cervical cord compression and cervical ossification of the posterior longitudinal ligament with a minimum 2-year follow-up[J].Medicine (Baltimore),2017,96(45):e8332.
[10] SHEEN J J,JEON S R.Midline splitting cervical laminoplasty using allogeneic bone spacers:Comparison of fusion rates between cervical spondylotic myelopathy and ossification of posterior longitudinal ligament[J].Korean J Neurotrauma,2014,10(2):60-65.
[11] 张本,侯铁胜,沈洪兴,等.颈椎后纵韧带骨化症的手术疗效及影响因素分析[J].广东医学,2013,34(23):3564-3568.
[12] 邓元,倪斌.颈椎矢状序列测量方法的研究进展[J].中国脊柱脊髓杂志,2014,24(7):655-659.
[13] 王瑞军,高春华,姜昊,等.颈椎间盘神经分布的研究进展[J].中华灾害救援医学,2017,5(4):230-234.
[14] WANG P,LIU X,ZHU B,et al.Association of IL17RC and COL6A1 genetic polymorphisms with susceptibility to ossification of the thoracic posterior longitudinal ligament in Chinese patients[J].J Orthop Surg Res,2018,13(1):109.
[15] 王亚楠,侯海涛,邵诗泽,等.不同手术入路治疗颈椎后纵韧带骨化症疗效的Meta分析[J].中国矫形外科杂志,2016,24(15):1384-1389.
[16] LU T,LIU C,YANG B,et al.Single-Level anterior cervical corpectomy and fusion using a new 3D-printed anatomy-adaptive titanium mesh cage for treatment of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament:A retrospective case series study[J].Med Sci Monit,2017,23:3105-3114.
[17] HYUN S J,KIM H K,KIM K J,et al.Posterior trans-dural repair of iatrogenic spinal cord herniation after resection of ossification of posterior longitudinal ligament[J].Asian Spine J,2016,10(2):355-359.
[18] CHOI B W,HUM T W.Significance of intramedullary high signal intensity on magnetic resonance imaging in patients with cervical ossification of the posterior longitudinal ligament[J].Clin Orthop Surg,2015,7(4):465-469.
[19] GU Y,SHI J,CAO P,et al.Clinical and imaging predictors of surgical outcome in multilevel cervical ossification of posterior longitudinal ligament:An analysis of 184 patients[J].PLoS One,2015,10(9):e0136042.
[20] 张少华,施宗祥.颈前与颈后入路减压内固定治疗多节段脊髓型颈椎病临床疗效[J].中国医学工程,2016,24(10):50-51.
[21] 石云志,刘泉.长节段颈椎后纵韧带骨化症修复:后路椎板切除植骨内固定与前路椎体次全切除减压的比较[J].中国组织工程研究,2014,18(53):8601-8606.
[22] HASHIZUME H,KONNO S,TAKESHITA K,et al.Japanese orthopaedic association back pain evaluation questionnaire (JOABPEQ) as an outcome measure for patients with low back pain:reference values in healthy volunteers[J].J Orthop Sci,2015,20(2):264-280.
[23] YOSHII T,SAKAI K,HIRAI T,et al.Anterior decompression with fusion versus posterior decompression with fusion for massive cervical ossification of the posterior longitudinal ligament with a ≥ 50% canal occupying ratio:a multicenter retrospective study[J].Spine J,2016,16(11):1351-1357.
[24] 周鑫,马向阳,杨进城,等.颈椎前路术后早期急性并发症的原因及治疗[J].中国矫形外科杂志,2015,23(23):2198-2201.
[25] 郭鹏年,董乐乐,刘瑞,等.颈椎前路手术并发脑脊液漏的原因分析和治疗体会[J].中国骨与关节损伤杂志,2016,31(7):731-732.
[26] 贾斌,周晓庆,张传健,等.两种颈后路手术治疗多节段脊髓型颈椎病术后C5神经根麻痹的效果比较[J].中国医药导报,2016,13(15):85-88.

服务与反馈:
文章下载】【发表评论】【查看评论】【加入收藏
提示:您还未登录,请登录!点此登录
您是第 744686 位访问者


 ©《现代医学》编辑部
联系电话:025-83272481;83272479
电子邮件: xdyx@pub.seu.edu.cn

苏ICP备09058541