食管癌患者放疗后疼痛与生活质量相关性分析-现代医学

食管癌患者放疗后疼痛与生活质量相关性分析

单位：1. 扬州大学附属医院肿瘤科, 江苏扬州 225001;
2. 江苏省人民医院老年科, 江苏南京 210029

分类号：R735.1;R730.55

出版年·卷·期（页码）：2019·38·第十一期（1395-1398）

摘要：

目的：调查食管癌患者放疗后的疼痛程度，了解食管癌放疗后疼痛对患者生活质量的影响，为临床止痛治疗提供依据。方法：对2015年12月至2016年12月入住扬州大学附属医院的80例食管癌根治性放疗患者采用简明疼痛调查表（BPI）评估放疗后疼痛对生活质量的影响。结果：发生轻度疼痛29例，占36.25%；中度疼痛39例，占48.75%；重度疼痛12例，占15%。肿瘤位于食管上段的疼痛较中下段重，差异有统计学意义（P<0.05）；放疗后的疼痛与年龄、性别、分期无关。放疗后疼痛与放射性损伤呈正相关（r=0.627，P<0.01），与内镜下表现也呈正相关（r=0.339，P<0.01）。疼痛越严重，对患者的日常生活、情绪、活动能力、睡眠和生活乐趣的影响也越大（P<0.01）。结论：放疗后食管癌患者存在明显的疼痛，对生活质量产生影响。加强对食管癌患者放疗期间疼痛的管理，及时有效地评估疼痛程度，给予疼痛处理，可提高患者的生活质量。

Objective: To investigate the degree of pain after esophageal cancer radiotherapy, to understand the impact of pain after radiotherapy on the quality of life of patients with esophageal cancer, provide the basis for the clinical analgesic treatment. Methods: A brief Pain Questionnaire (BPI) was used for 80 patients with radical radiotherapy for esophageal cancer admitted between December 2015 and December 2016. The patient's post-radiotherapy pain on the quality of life was assessed. Results: Mild pain occurred in 29 cases, accounting for 36.25%; moderate pain in 39 cases accounted for 48.75%; severe pain in 12 cases accounted for 15%. Tumor located in the upper esophagus was more advanced than the middle and lower esophagus, with a significant difference (P<0.05). There was no significant difference of age, sex and staging in the pain after radiotherapy. After radiotherapy, pain and radiation injury were positively correlated. There was a significant statistical difference (P<0.01). Post-radiotherapy pain and endoscopic performance was also positively correlated. The difference was statistically significant (P<0.01). The study also showed that pain was severe and had a greater effect on patient's daily life, mood, mobility, sleep and life pleasure with significant differences (P<0.01). Conclusion: There is obvious pain in patients with esophageal cancer after radiotherapy, which has an impact on the quality of life. It is necessary to strengthen the management of pain during radiotherapy, timely and effectively evaluate the degree of pain, give pain management, and improve the quality of life of patients.

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