子宫动脉栓塞术治疗子宫肌瘤术后复发的危险因素分析-现代医学

子宫动脉栓塞术治疗子宫肌瘤术后复发的危险因素分析

单位：1. 延安大学附属医院产科, 陕西延安 716000;
2. 陕西省中医医院介入科, 陕西西安 710000

分类号：R737.33

出版年·卷·期（页码）：2019·47·第八期（983-986）

摘要：

目的：探讨子宫动脉栓塞术（UAE）治疗子宫肌瘤术后复发情况及影响复发的相关因素。方法：收集325例采用UAE治疗的子宫肌瘤患者临床资料及随访情况，记录所有患者年龄、初潮年龄、体重指数（BMI）、肌瘤家族史、肌瘤数目、肌瘤最大直径、肌瘤位置、肌瘤血供、栓塞剂类型及术后妊娠等临床资料，及术后随访子宫肌瘤复发情况，采用单因素分析法及多因素Logistic回归分析法分析UAE治疗子宫肌瘤术后复发的危险因素。结果：325例子宫肌瘤患者共随访到268例（71.74%），失访57例（28.26%），随访者和失访者各基线资料比较差异均无统计学意义（均P>0.05）。268例患者1年累计复发率3.1%，术后2年累计复发率8.6%，术后3年累计复发率10.4%。单因素分析结果显示复发组和非复发组比较，两组肌瘤个数、肌瘤最大直径和肌瘤位置的差异具有统计学意义（均P<0.05）。多因素分析结果显示肌瘤个数≥ 2个与子宫肌瘤患者UAE术后复发相关（OR=2.432，95%CI 1.307~10.670，P=0.001）。结论：肌瘤个数≥ 2个是子宫肌瘤患者UAE术后复发的独立危险因素。

Objective:To investigate the risk factors of recurrence after uterine artery embolization (UAE) in patients with uterine fibroid. Methods:A total of 325 patients with uterine fibroid who treated by UAE were included in the study. In order to identify the factors of recurrence, the characteristics of age, menarche age, body mass index (BMI), family history of fibroid, the number of fibroid, the biggest fibroids diameter, the location of fibroid, blood supply patterns of myoma, patterns of embolic agent and the pregnancy and delivery after UAE were compared and analyzed. The risk factors of recurrence were analyzed by univariate analysis and multiariable logistic regression analysis. Results:There were no differences in the factors before and during operation in the followed-up of 268 patients and 57 patients lost in the survey (all P>0.05). In univariate analysis, there was a significant difference between recurrence group and non-recurrence group in the number of fibroid, the biggest fibroids diameter, the location of fibroid (all P<0.05). Multiariable logistic regression analysis showed that the number of fibroid more than 2 was associated with recurrence (OR=2.432, 95%CI 1.307-10.670, P=0.001). Conclusion:For patients with uterine fibroid, the number of fibroid more than 2 is an independent risk factors of recurrence after UAE.

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