[1] GOMEZ I G,NAKAGAWA N,DUFFIELD J S.MicroRNAs as novel therapeutic targets to treat kidney injury and fibrosis[J].Am J Physiol Renal Physiol,2016,310(10):F931-F944.
[2] ZHANG L,WANG F,WANG L,et al.Prevalence of chronic kidney disease in China:a cross-sectional survey[J].Lancet,2012,379(9818):815-822.
[3] 汤涛涛,吕林莉,刘必成.microRNAs与肾脏纤维化[J].东南大学学报:医学版,2014,33(6):788-793.
[4] XU X,KRIEGEL A J,LIU Y,et al.Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21[J].Kidney Int,2012,82(11):1167-1175.
[5] CAO Y,HU J,SUI J,et al.Quercetin is able to alleviate TGF-β-induced fibrosis in renal tubular epithelial cells by suppressing miR-21[J].Exp Ther Med,2018,16(3):2442-2448.
[6] ZHONG X,CHUNG A C,CHEN H Y,et al.Smad3-Mediated upregulation of miR-21 promotes renal fibrosis[J].J Am Soc Nephrol,2011,22(9):1668-1681.
[7] CHAU B N,XIN C,HARTNER J,et al.MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways[J].Sci Transl Med,2012,4(121):121ra118.
[8] WANG J,GAO Y,MA M,et al.Effect of miR-21 on renal fibrosis by regulating MMP-9 and TIMP1 in kk-ay diabetic nephropathy mice[J].Cell Biochem Biophys,2013,67:537-546.
[9] DU X,SHIMIZU A,MASUDA Y,et al.Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy[J].Lab Invest,2012,92:1149-1160.
[10] LAI J Y,LU J,O'CONNOR C,et al.MicroRNA-21 in glomerular injury[J].J Am Soc Nephrol,2015,26:805-816.
[11] GOMEZ I G,NAKAGAWA N,DUFFIELD J S.MicroRNAs as novel therapeutic targets to treat kidney injury and fibrosis[J].Am J Physiol Renal Physiol,2016,310:F931-944.
[12] DENBY L,RAMDAS V,LU R,et al.MicroRNA-214 antagonism protects against renal fibrosis[J].J Am Soc Nephrol,2014,25:65-80.
[13] LI L M,HOU D X,GUO Y L,et al.Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes[J].J Immunol,2011,186:2552-2560.
[14] WANG X,SHEN E,WANG Y,et al.Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions[J].Sci Rep,2016,6:1-11.
[15] HU X,WANG J,HE W,et al.MicroRNA-433 targets AKT3 and inhibits cell proliferation and viability in breast cancer[J].Oncol Lett,2018,15(3):3998-4004.
[16] LI R,CHUNG A C,DONG Y,et al.The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-beta/Smad3-Azin1 pathway[J].Kidney Int,2013,84:1129-1144.
[17] CHEN Y,SONG Y X,WANG Z N,et al.The microRNA-148/152 family:multi-faceted players[J].Mol Cancer,2013,12:1-8.
[18] AGARWAL P,SRIVASTAVA R,SRIVASTAVA A K,et al.miR-135a targets IRS2 and regulates insulin signaling and glucose uptake in the diabetic gastrocnemius skeletal muscle[J].Biochim Biophys Acta,2013,1832:1294-1303.
[19] HE F,PENG F F,XIA X,et al.MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1[J].Diabetologia,2014,57:1726-1736.
[20] NITTA K,SHI S,NAGAI T,et al.Oral administration of N-acetyl-seryl-aspartyl-lysyl-proline ameliorates kidney disease in both type 1 and type 2 diabetic mice via a therapeutic regimen[J].Bio Med Res Int,2016,9172157:1-11.
[21] PARK J T,KATO M,LANTING L,et al.Repression of let-7 by transforming growth factor-beta1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions[J].Am J Physiol Renal Physiol,2014,307:F1390-1403.
[22] WANG B,JHA J C,HAGIWARA S,et al.Transforming growth factor-beta1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b[J].Kidney Int,2014,85:352-361.
[23] THORNTON J E,CHANG H M,PISKOUNOVA E,et al.Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11(TUT4) and Zcchc6(TUT7)[J].RNA,2012,18:1875-1885.
[24] CHEN P Y,QIN L,BARNES C,et al.FGF regulates TGF-beta signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression[J].Cell Rep,2012,2:1684-1696.
[25] NAGAI T,KANASAKI M,SRIVASTAVA S P,et al.N-acetyl-seryl-aspartyl-lysyl-proline inhibits diabetes-associated kidney fibrosis and endothelial-mesenchymal transition[J].Bio Med Res Int,2014,696475:1-12.
[26] BRENNAN E P,NOLAN K A,BORGESONE,et al.Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFbetaR1[J].J Am Soc Nephrol,2013,24:627-637.
[27] LV L L,CAO Y H,NI H F,et al.MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis[J].Am J Physiol Renal Physiol,2013,305:F1220-1227.
[28] QIN W,CHUNG A C,HUANG X R,et al.TGF-beta/Smad3 signaling promotes renal fibrosis by inhibiting miR-29[J].J Am Soc Nephrol,2011,22:1462-1474.
[29] LIN C L,LEE P H,HSU Y C,et al.MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction[J].J Am Soc Nephrol,2014,25:1698-1709.
[30] CHE T H,LEE C,CHIU C T,et al.Circulating microRNA-196a is an early gastric cancer biomarker[J].Oncotarget,2017,9(12):10317-10323.
[31] MENG J,LI L,ZHAO Y,et al.MicroRNA-196a/b mitigate renal fibrosis by targeting TGF-β receptor 2[J].J Am Soc Nephrol,2016,27:3006-3021.
[32] SHI S,YU L,ZHANG T,et al.Smad2-dependent downregulation of miR-30 is required for TGF-beta-induced apoptosis in podocytes[J].PLoS One,2013,8:e75572.
[33] WU J,ZHENG C,FAN Y,et al.Downregulation of microRNA-30 facilitates podocyte injury and is prevented by glucocorticoids[J].J Am Soc Nephrol,2014,25:92-104.
[34] DUISTERS R F,TIJSEN A J,SCHROEN B,et al.miR-133 and miR-30 regulate connective tissue growth factor:implications for a role of microRNAs in myocardial matrix remodeling[J].Circ Res,2009,104:170-178.
[35] BURK U,SCHUBERT J,WELLNER U,et al.A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells[J].EMBO Rep,2008,9:582-589.
[36] WANG B,KOH P,WINBANKS C,et al.miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expression[J].Diabetes,2011,60:280-287.
[37] OBA S,KUMANO S,SUZUKI E,et al.miR-200b precursor can ameliorate renal tubulointerstitial fibrosis[J].PLoS One,2010,5:e13614.
[38] PUTTA S,LANTING L,SUN G,et al.Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy[J].J Am Soc Nephrol,2012,23:458-469.
[39] CHUNG A C,HUANG X R,MENG X,et al.miR-192 mediates TGF-beta/Smad3-driven renal fibrosis[J].J Am Soc Nephrol,2010,21:1317-1325.
[40] KATO M,ZHANG J,WANG M,et al.MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors[J].Proc Natl Acad Sci,2007,104:3432-3437.
[41] KATO M,ARCE L,WANG M,et al.A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells[J].Kidney Int,2011,80:358-368.
[42] KRUPA A,JENKINS R,LUO D D,et al.Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy[J].J Am Soc Nephrol,2010,21:438-447.
[43] LANFORD R E,HILDEBRANDT-ERIKSEN E S,PETRI A,et al.Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection[J].Science,2010,327:198-201.
[44] TRIONFINI P,BENIGNI A,REMUZZI G.MicroRNAs in kidney physiology and disease[J].Nat Rev Nephrol,2015,11:23-33. |
