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维生素D与肥胖相关炎症及胰岛素抵抗的研究进展
作者:李波  于萍 
单位:哈尔滨医科大学附属第二医院 内分泌科三病房, 黑龙江 哈尔滨 150086
关键词:维生素D 低度炎症 肥胖 胰岛素抵抗 2型糖尿病 综述 
分类号:R589.2;R587.1
出版年·卷·期(页码):2019·47·第三期(368-371)
摘要:

维生素D是参与钙磷平衡调控的关键因素,最近研究表明其与低度炎症、肥胖和胰岛素抵抗的发病机制相关。维生素D增加了一些肥胖相关抗炎细胞因子的产生并减少了一些促炎细胞因子的释放。因为慢性炎症在代谢综合征、肥胖症和糖尿病中有重要作用,所以许多研究者假设维生素D参与这些疾病的发生发展。维生素D的状态可以改变促炎和抗炎细胞因子之间的平衡,从而影响胰岛素作用、脂质代谢和脂肪组织的功能和结构。作者综述了维生素D浓度与促炎症标志物、胰岛素抵抗和肥胖的关系。

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