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肠道菌群失调对类风湿关节炎发生发展的影响及机制研究
作者:陈梦妮1  于泓1  余丽梅2 
单位:1. 遵义医学院附属医院 肾病风湿科, 贵州 遵义 5603003;
2. 遵义医学院附属医院 细胞工程室, 贵州 遵义 5603003
关键词:类风湿关节炎 肠道菌群 失调 机制 
分类号:R593;R372
出版年·卷·期(页码):2019·47·第二期(195-198)
摘要:

肠道菌群在调节内皮生长分化、保护细胞以及维持免疫稳态等方面具有比较重要的作用。近几年的研究报道,肠道菌群失调可能会导致多种骨关节疾病的发生。肠道菌群失调而引起机体产生炎症反应等可能参与了类风湿关节炎的发病机制,临床口服莫西沙星和低淀粉饮食可以减轻类风湿关节的症状,此外乳酸菌类制剂在临床治疗类风湿关节炎方面也具有良好的效果。从而在临床上可以通过靶向调节肠道菌群失调而治疗类风湿关节炎患者,提供了理论新方向。

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