Objective: To study the application values of tirofiban utraselection percutaneous coronary intervention(PCI) in patients with ST segment elevation myocardial infarction (STEMI). Methods: A total of 296 patients with STEMI who were treated in our hospital from June 2015 to December 2016 were screened.Using random number table method, the patients were devided into 3 groups:91 patients(group A) were treated with ultraselective coronary artery administration, 91 patients(group B) were treated with conventional coronary artery administration (B group), and 107 patients(group C) were given conventional intravenous administration.The myocardial infarction thrombolytic blood flow classification,ST segment elevation drop rate and the incidence of adverse cardiovascular events during follow-up of3 months were compared among the three groups. Results: There were significant differences in TIMI grade Ⅲ rates of the three groups after PCI,from high to low was group C>group B> group A (P<0.05).The complete regression rate of ST segment of the group A was significantly higher than those of group B and group C(P<0.05), butthere was no significant difference between group B and group C (χ2=0.002, P>0.05).During the follow-up period, the incidence of related clinical adverse events was significantly lower in the group A than the other two groups(P<0.05),while there was no significant difference between the group B and group C (χ2=1.003, P>0.05). Conclusions: The effect of tirofiban utraselection PCI on patients with acute STEMI can significantly improve cardiac function, and reduce the occurrence of postoperative clinical adverse events.
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