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基于血管内超声探究冠状动脉病变血管数与最小管腔面积的相关性
作者:章晓国1  王仁云1  虞春雷1  刘晓恺1  汤成春1  丁建东1  靳激扬2 
单位:1. 东南大学附属中大医院 心血管内科, 江苏 南京 210009;
2. 东南大学附属中大医院 影像科, 江苏 南京 210009
关键词:冠心病 血管内超声 最小管腔面积 
分类号:R541.4;R445.1
出版年·卷·期(页码):2018·46·第十二期(1388-1391)
摘要:

目的:通过血管内超声(IVUS)测定左前降支近中段病变的最小管腔面积(MLA)及斑块负荷,探究冠心病患者病变血管数量与MLA及斑块负荷的关系。方法:连续、回顾性选取接受冠状动脉造影并同时对左前降支行IVUS检查的冠心病患者91例,男62例,女29例,将其分为单支病变组50例和多支病变组41例,收集其临床资料、病史及实验室检查结果,进行相关性分析。结果:单支病变组与多支病变组之间MLA及斑块负荷差异均有统计学意义(P<0.001)。冠心病患者病变血管数与MLA呈负相关(r=-0.413,P<0.001),病变血管数与斑块负荷呈正相关(r=0.359,P<0.001)。结论:冠心病患者病变血管数与MLA及斑块负荷存在相关性。

Objective: To explore the association between the number of stenotic coronary arteries and minimum lumen area (MLA) or plaque burden from the intravascular ultrasound (IVUS) of left anterior descending artery.Methods: A total of 91 consecutive patients who underwent both coronary angiography and IVUS of left anterior descending artery were retrospectively enrolled in this study,including 62 males and 29 females.These patients were further divided into single-vessel disease group (50 cases) and multi-vessel disease group (41 cases).Their clinical data,medical history and laboratory test results were collected and analyzed by correlation analysis.Results: There were statistically significant differences in MLA and plaque burden between the single-vessel disease group and the multi-vessel disease group (P<0.001).The number of stenotic artery in patients with coronary heart disease was negatively correlated with MLA(r=-0.413,P<0.001).The number of stenotic arteries was positively correlated with plaque burden (r=0.359,P<0.001).Conclusion: There is a correlation between the number of stenotic artery and MLA or plaque burden.

参考文献:

[1] TONINO P A,FEARON W F,de BRUYNE B,et al.Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation[J].J Am CollCardiol,2010,55(25):2816-2821.
[2] 刘传芬,王伟民,刘健,等.血管内超声在冠状动脉临界病变诊断和介入治疗中的应用[J].中国循环杂志,2011(1):15-18.
[3] 中国高血压防治指南修订委员会.中国高血压防治指南2010[J].中华心血管病杂志,2011(7):579-616.
[4] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2017年版)[J].中华糖尿病杂志,2018(1):4-67.
[5] 顾菲菲,吕树铮,陈韵岱,等.血管内超声技术对不稳定性心绞痛患者冠状动脉临界病变形态学评价[J].中国介入心脏病学杂志,2011,19(3):125-128.
[6] 倪志超,马根山.血管内超声在冠心病中的应用价值[J].东南大学学报(医学版),2015,34(4):636-640.
[7] 血管内超声在冠状动脉疾病中应用的中国专家共识专家组.血管内超声在冠状动脉疾病中应用的中国专家共识(2018)[J].中华心血管病杂志,2018(5):344-351.
[8] KANG S J,LEE J Y,AHN J M,et al.Validation of intravascular ultrasound-derived parameters with fractional flow reserve for assessment of coronary stenosis severity[J].Circ Cardiovasc Interv,2011,4(1):65-71.
[9] KOO B K,YANG H M,DOH J H,et al.Optimal intravascular ultrasound criteria and their accuracy for defining the functional significance of intermediate coronary stenoses of different locations[J].JACC Cardiovasc Interv,2011,4(7):803-811.
[10] HIBI K,KIMURA K,UMEMURA S.Clinical utility and significance of intravascular ultrasound and optical coherence tomography in guiding percutaneous coronary interventions.[J].Circ J,2014,79(1):24-33.
[11] 张英,刘健,王伟民,等.基于血管内超声评价冠状动脉临界病变的相关危险因素分析[J].中国介入心脏病学杂志,2015,23(7):371-375.
[12] 周华,王娟,何晓燕,等.血管内超声观察急性冠脉综合征非显著狭窄的病变斑块破裂及形态特点[J].重庆医学,2013,42(17):1943-1945.
[13] 胡小莲,刘骏,叶天舟,等.冠状动脉粥样硬化程度与外周动脉粥样硬化的相关性[J].现代医学,2015,43(8):1043-1045.
[14] 陈中璞,陈忠,马根山,等.急性心肌梗死患者冠状动脉病变程度的危险因素分析[J].现代医学,2009,37(4):277-279.

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