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10周有氧运动干预疗法对提高炎症性肠病患者生活质量作用的临床研究
作者:丁文琴1  陈阿粉1  尚星辰2  卞秋桂1 
单位:1. 南京医科大学第一附属医院 消化科, 江苏 南京 210029;
2. 南京医科大学 护理学院, 江苏 南京 211166
关键词:有氧运动 炎症性肠病 生活质量 
分类号:R574.62
出版年·卷·期(页码):2018·46·第十二期(1331-1335)
摘要:

目的:探讨10周有氧运动疗法对改善炎症性肠病患者生活质量的作用。方法:选取2017年1月至2018年6月在南京医科大学第一附属医院消化科就诊的75例炎症性肠病(包括克罗恩病和溃疡性结肠炎)患者作为研究对象,将患者随机分为对照组和运动组。运动组干预方式为有氧慢跑,前5周运动强度为45%~55%最大摄氧量对应的心率,后5周为55%~65%最大摄氧量对应心率。试验期间遵照医嘱常规服用抗炎症性肠病药物,不得更换药物的种类和剂量,试验过程中记录用药情况、运动执行情况、不良反应、失访者和失访原因。末次试验次日再次进行体检及血清学检查以便于对照研究。结果:与干预前测试的基线值相比,运动组经过10周的运动后炎症性肠病调查问卷(IBDQ)评分提高(P<0.05);此外,IBDQ的亚项目情感功能、社会功能、肠道功能及全身功能10周后的评分均较基线值显著提高(P<0.05)。对照组10周日常生活后其IBDQ总评分与基线值相比也有显著提高(P<0.05),而细化到4个亚项,除了情感功能得分,其余3个亚项的得分均比基线值有显著性提高(P<0.05)。10周后运动组和对照组的IBDQ总评分比较差异无统计学意义(P>0.05)。结论:患者能够耐受的适度的运动对于稳定期的炎症性肠病患者利大于弊。有氧运动干预对患者生活质量的提高有积极的作用,而且对患者生活质量中社会功能部分的提高效果更明显。

Objective: To investigate the impact of a Ten-week aerobic physical intervention on health-related quality of life in patients with inflammatory bowel disease. Methods: 75 cases of patients with inflammatory bowel disease were selected and randomized assigned into exercise intervention group and control group. Health-related quality of life, symptoms, and inflammation were assessed at baseline and after 10 weeks. Results: After 10 weeks the IBDQ score was significantly higher than that of baseline(P<0.05) both in control group and in exercise intervention group. After 10 weeks exercise, the total IBDQ score showed no significant difference between exercise intervention group and control group(P>0.05). Conclusion: The amount of exercise used in the study is feasible in patients with stable inflammatory bowel disease. It indicates that aerobic physical activity may improve quality of life, especially in social well-being.

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