Objective:Computed tomography-guided radiofrequency ablation (CT-RFA) and laparoscopic RFA (L-RFA) have been used to treat intrahepatic recurrent small hepatocellular carcinoma (HCC) abutting the diaphragmatic dome. However, the therapeutic safety, efficacy, and hospital expense have never been compared between the two techniques due to the scarcity of the cases. Methods:In this retrospective study, 116 patients were divided into two groups with a total of 151 local recurrent HCC lesions abutting the diaphragm.We compared overall survival (OS), local tumor progression (LTP), postoperative complications, and hospital stay and expense between the two groups. Results:Our findings revealed no significant differences in 5-year OS (36.7% vs 44.6%, P=0.428 9) or 5-year LTP (73.3% vs 67.9%, P=0.889 7) between CT-RFA and group L-RFA. The overall hospital stay (2.8 days vs 4.1 days, P<0.000 1) and cost (￥19 217.6 vs ￥25 553.6,P<0.000 1) were significantly lower in group CT-RFA in comparison with group L-RFA. Conclusion:CT-RFA is relatively easy and economic for recurrent small HCC abutting the diaphragm, and both CT-RFA and L-RFA are effective techniques.
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