后循环脑梗死患者影像检查检出椎动脉颅内钙化的相关因素-现代医学

后循环脑梗死患者影像检查检出椎动脉颅内钙化的相关因素

单位：1. 中国人民解放军252医院神经内科, 河北保定 071000;
2. 保定市第一中心医院神经内三科, 河北保定 071000

分类号：R743

出版年·卷·期（页码）：2018·46·第四期（386-389）

摘要：

目的：探讨后循环脑梗死患者影像检查检出椎动脉颅内钙化的相关因素。方法：选择后循环脑梗死患者200例设为观察组，同期入院健康体检者200例设为对照组；采用64排螺旋CT对研究对象进行常规检查，统计两组临床资料，采用全自动生化分析仪测定两组血钙、血磷、尿素氮、血脂及白细胞水平，对上述因素进行单因素及多因素Logistic回归分析，分析后循环脑梗死患者影像检查检出椎动脉钙化的相关因素。结果：观察组与对照组均检出椎动脉颅内钙化，观察组发生率高于对照组（P<0.05）；观察组椎动脉颅内钙化患者有高血压史、糖尿病史、吸烟者比例及总胆固醇、三酰甘油、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇水平均高于椎动脉颅内无钙化患者（P<0.05）；多因素Logistic回归分析显示，后循环脑梗死患者影像检查椎动脉颅内钙化检出率与高血压、糖尿病、吸烟及高血脂关系密切（P<0.05）。结论：后循环脑梗死患者椎动脉颅内钙化发生率明显高于健康人群，加强后循环脑梗死患者64排螺旋CT检查可评估患者疾病严重程度，为临床治疗提供依据。

Objective: To investigate the related factors of intracranial calcification of vertebral artery detected by imaging in patients with posterior circulation cerebral infarction. Methods: A total of 200 patients with posterior circulation infarction admitted in our hospital were selected as observation group, and 200 healthy subjects were selected as control group. The patients were routinely examined by 64-slice spiral CT. The clinical data of the two groups were statistically analyzed. The levels of serum calcium, phosphorus, blood urea nitrogen(BUN) and leukocyte were measured by automatic biochemical analyzer. Multivariate Logistic regression analysis was used to analyze the related factors of vertebral artery calcification after imaging in patients with posterior circulation cerebral infarction. Results: Intracranial calcification of the vertebral artery was detected in the 64-slice spiral CT examination in the observation group and the control group. The incidence of intracranial calcification of the vertebral artery in the observation group was higher than that in the control group(P<0.05). History of hypertension and diabetes, smoking and levels of TC, TG, LDL-C and HDL-C were all higher in patients with intracranial calcification than those without intracranial calcification in vertebral artery(P<0.05). Multivariate Logistic regression analysis showed that the incidence of intracranial calcification of vertebral artery in patients with posterior circulation cerebral infarction was closely correlated with hypertension, diabetes, smoking and hyperlipidemia(P<0.05). Conclusion: The incidence of intracranial calcification of vertebral artery in patients with posterior circulation cerebral infarction is significantly higher than that of healthy people. It is of great value to popularize the application of 64-slice spiral CT in patients with posterior circulation cerebral infarction to evaluate the severity of disease and provide imaging basis for clinical treatment.

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