肝硬化患者门静脉血栓形成危险因素分析-现代医学

肝硬化患者门静脉血栓形成危险因素分析

单位：安徽医科大学附属巢湖医院, 安徽巢湖 238000

分类号：R575.2

出版年·卷·期（页码）：2018·46·第三期（290-293）

摘要：

目的：探究肝硬化患者门静脉血栓形成的多种危险因素。方法：收集肝硬化患者140例，其中肝硬化合并门静脉血栓形成（PVT）的共有70例（PVT组），肝硬化不合并PVT的70例作为对照组。利用单因素分析和Logistic回归模型对两组资料进行对比研究。结果：切脾史、血红蛋白降低、D-二聚体升高和血小板升高的病例在PVT组明显高于对照组（P<0.05）。结论：切脾史、血红蛋白降低、D-二聚体升高、血小板升高是肝硬化合并门静脉血栓形成的独立危险因素。临床上对于有以上独立危险因素的肝硬化患者应注意排除是否合并有门静脉血栓形成，并可进行适当的预防性治疗。

Objective: To explore the risk factors for portal vein thrombosis in patients with liver cirrhosis.Methods: A total of 140 patients with cirrhosis were collected, including 70 cases of cirrhosis complicated with portal vein thrombosis (PVT) as the experimental group, and 70 cases of cirrhosis without PVT as the control group.Two groups of related clinical data were collected. Single factor analysis and Logistic regression model were used to compare the two groups of data. Results: The history of appendectomy, the decrease of hemoglobin, the increase of D-dimer and the increase of platelet were significantly higher in the experimental group than those in the control group (P<0.05).Conclusion: The appendectomy history, hemoglobin reduction, D-dimer and platelet increase are independent risk factors for hepatic cirrhosis complicated with PVT. Thecirrhosispatients with the above risk factors should beexcluded from the merger of portal vein thrombosis, and can be taken appropriate preventive treatment.

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