Objective:To explore the value ofultra fast ultrasound imaging plus wave velocity(ufPWV) in evaluationthe correlation between body mass index(BMI) and carotid arterial stiffness. Methods:A total of 277 subjects were enrolled in this study, the height, weight, blood pressure,blood lipid,blood glucose(GLU) were measured, and BMI was calculated.The carotid intima-media thickness(IMT) was detected and then the ufPWV technology was used to assess the beginning-systole pulse wave velocity (BS) and end-systole pulse wave velocity (ES).According to BMI, the subjects were divided into three groups:76 cases(151 carotid arteries) in the overweightgroup,22 cases (43 carotid arteries) in the obesity group and 179 cases(357 carotidarteries) in the normal group. Rseults:(1)The difference of ES between the normal group and the overweight group was statistically significant(P<0.001),the differences of BS and IMT between the normal group and the overweight group were not statistically significant(P>0.05). The differences of BS,ES and IMT between the obesity group and the normal group or the overweight group were statistically significant (all P<0.05).(2)By using multivariate linear regression analysis to control confounding factors, including age, blood pressure and so on, the differences of BS,ES and IMT between the obesity group and the normal group or the overweight group were still statistically significant (P<0.05).(3)The correlations between BMI and BS, ES, IMT were analyzed, the correlation coefficient of ES was larger than those of of BS or IMT. Conclusions:ufPWV technology is more sensitive in showing the correlation between vascular elasticity and BMI than IMT. Itcan be used as a new effective method for quantitative evaluation of arterial elasticity and atherosclerosis. |