Objective: Bronchoscopic argon plasma coagulation analysis (APC) combined with cryotherapy in the treatment of central type lung cancer with airway obstruction.Method: From December 2014 to November 2016, 120 cases of lung cancer patients with airway obstruction treated in our hospital were divided into control group and observation group according to the patients' willingness, with 60 patients in each group. The control group was given conventional chemotherapy, and the observation group was treated with APC under the bronchoscope combined with freezing interventional therapy on the basis of routine chemotherapy. The clinical effect, survival time, Karnofsky score and safety of the two groups were observed and evaluated. Result: In the observation group, 22 out of 60 cases had completely effect (36.7%),32 cases had effect (53.3%), the total effectiveness was 90%, significantly better than that of the control group (P<0.05). The patients' survival time and Karnofsky score were significantly higher than those in the control group, the difference was statistically significant (P<0.05).The survival time and Karnofsky score of the observation group were higher than those of the control group, the difference was statistically significant (P<0.05). APC combined with cryoablation was safe. Conclusion: Bronchoscopic argon plasma coagulation combined with cryotherapy in the treatment of central type lung cancer with airway obstruction, when compared with chemotherapy, has more prominent curative effect, better safety and longer survival time, thus it is worthy of clinical application. |
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