艾司洛尔治疗心肌梗死后交感风暴患者的临床研究-现代医学

艾司洛尔治疗心肌梗死后交感风暴患者的临床研究

单位：1. 陕西省人民医院功能检查科, 陕西西安 710068;
2. 陕西省人民医院心血管内一科, 陕西西安 710068

分类号：R541

出版年·卷·期（页码）：2017·36·第五期（669-672）

摘要：

目的：探讨艾司洛尔对急性心肌梗死（AMI）后交感风暴患者的治疗效果。方法：回顾性分析50例在我院接受AMI治疗后发生交感风暴患者的临床资料，并根据其治疗方式分为对照组和观察组，其中对照组给予电复律、胺碘酮或利多卡因进行治疗，观察组在此基础上静脉应用艾司洛尔。观察两组患者治疗前后心率、血压的变化，比较两组患者电复律使用次数、心功能和并发症发生率的差异。结果：治疗后观察组心率、收缩压和舒张压低于对照组（均P < 0.05），心功能优于对照组（P < 0.05），电复率次数明显比对照组少（P < 0.05）；观察组心动过缓、低血压和心功能不全等并发症的发生率明显低于对照组（均P < 0.05）。结论：艾司洛尔对AMI治疗后发生交感风暴患者有较好的治疗效果，可明显改善患者血压和心率，减少电复律次数，具有较好的临床应用价值。

Objective: To investigate the therapeutic effects of esmolol on sympathetic storm patients caused by acute myocardial infarction (AMI).Methods: Clinical data of 50 patients who were treated in our hospital and had sympathetic stormcaused by AMI were analyzed retrospectively.The patients were divided into control group and observation group according the therapy method.The control group was treated with electric cardioversion, amiodarone or lidocaine,while the observation group was additionally treated with intravenous esmolol administration. Heart rate and blood pressure changes of the two groups were observed after treatment.The difference of cardioversion number and cardiac incidence were compared between the two groups.Results: After treatment,indexes of heart rate, systolic blood pressure and diastolic blood pressure in the observation group were lower than those in the control group (all P<0.05);observation group had a better cardiac condition than that of control group(P<0.05).Compared with the control group,the number of electrical complex rate in the observation group was significantly lower and the difference was statistically significant (P<0.05). Furthermore, the incidence of complications such as bradycardia,hypotension and cardiac insufficiency in the observation group was significantly lower than that in the control group. Conclusion: Esmolol has therapeutic effectiveness on sympathetic storm patients caused by AMI, which was embodied by significantly improving blood pressure,heart rate and reducing the electrical cardioversion times. Esmolol has better value in clinical applications.

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