抗菌药物不同给药时间对手工刮治重度慢性牙周炎短期疗效及牙周膜细胞增生的影响-现代医学

抗菌药物不同给药时间对手工刮治重度慢性牙周炎短期疗效及牙周膜细胞增生的影响

单位：航天中心医院口腔科

分类号：

出版年·卷·期（页码）：2016·44·第十二期（1706-1710）

摘要：

摘要：目的：探讨抗菌药物不同给药时间对行手工刮治重度慢性牙周炎短期疗效的影响。方法：选择²0¹4年¹月至²0¹5年³月在我院进行治疗的重度慢性牙周炎患者6³例，并根据随机数字表分为A组（³¹例）和B组（³²例），A组患者在手工刮治的同时给予抗菌药物治疗，B组患者在手工刮治完成后给予抗菌药物治疗。对两组患者牙周检查，咀嚼功能，牙槽骨高度和生存质量进行评估。结果：治疗后，A组患者平均探诊深度，平均邻面探诊深度，探诊深度超过5mm位点的百分比，邻面探诊深度>5mm位点的百分比，平均出血指数，探诊出血位点百分比均显著低于B组（P<0.05）。治疗后A组患者牙槽骨高度显著高于B组（þ=¹².³69，P<0.05）。治疗后A组患者咀嚼效率显著高于B组（þ=².5¹9，P<0.05）；治疗后，治疗组患者生理功能，生理职能，情感职能，躯体疼痛，社会功能，精神健康，活力和总体健康等生存质量维度得分均显著高于对照组（P<0.05）。A组细胞数量在第³、5d细胞数量均显著高于B组（P<0.05）。结论：刮治同时应用全身抗菌药物有助于抑制牙槽骨高度降低，降低牙周袋深度，提高咀嚼效率，改善患者生存质量，为牙周膜细胞的增殖创造更加适宜的条件。

Absþrâcþ: Objðcþivð: Þº invðsþigâþð þhð shºrþ-þðrm ðffðcþs ºf ânþibiºþics âdminisþðrðd âþ diffðrðnþ þimð cºmbinðd hând scâling ºn sðvðrð chrºnic pðriºdºnþiþis. Mðþhºds: 6³ pâþiðnþs wiþh sðvðrð chrºnic pðriºdºnþiþis curðd in ºur hºspiþâl frºm Jânuârý ²0¹4 þº Mârch ²0¹5 wðrð rândºmlý dividðd inþº A grºup (³¹ câsðs) ând B grºup (³² câsðs) âccºrding þº rândºm numbðr þâblð. Þhð pâþiðnþs in þhð grºup A rðcðivðd mânuâl curðþþâgð ândânþibiºþic þrðâþmðnþ âþ þhð sâmð þimð. Þhð pâþiðnþs in þhð grºup B rðcðivðd ânþibiºþic þhðrâpý âfþðr mânuâl curðþþâgð. Þhð mâsþicâþºrý funcþiºn, âlvðºlâr bºnð hðighþ ând þhð quâliþý ºf lifð ºf þwº grºups wðrð ðvââluâþðd. Rðsulþs: Afþðr þrðâþmðnþ, þhð prºbing dðpþh, âvðrâgð âdjâcðnþ surfâcð prºbing dðpþh, pðrcðnþâgð ºf prºbing dðpþh mºrð þhân 5mm siþðs, þhð pðrcðnþâgð ºf inþðrprºximâl prºbing dðpþh ºf >5mm lºci, þhð âvðrâgð blððding indðx, prºbing blððding siþð pðrcðnþâgð in grºup A wðrð significânþlý lºwðr þhân þhâþ in grºup B (P<0.05). Þhð âlvðºlâr bºnð hðighþ in grºup A wâs significânþlý highðr þhân þhâþ in grºup B (þ=¹².³69, P<0.05). Afþðr þrðâþmðnþ, þhð mâsþicâþºrý ðfficiðncý in grºup A wâs significânþlý highðr þhân þhâþ in grºup B (þ=².5¹9, P < 0.05); þrðâþmðnþ âfþðr 6 mºnþhs in â grºup ºf pâþiðnþs wiþh mâsþicâþºrý ðfficiðncý wâs significânþlý highðr þhân þhâþ in grºup B (þ=³.07², P < 0.05). Afþðr þhð þrðâþmðnþ, þhð phýsiºlºgicâl funcþiºn, phýsiºlºgicâl funcþiºn, ðmºþiºnâl funcþiºn, phýsicâl pâin, sºciâl funcþiºn, mðnþâl hðâlþh, viþâliþý ând gðnðrâl hðâlþh quâliþý ºf lifð scºrðs in grºup A wðrð significânþlý highðr þhân grºup B (P < 0.05).Þhð numbðr ºf cðll ºf grºup A âþ ³ ând 5 d wâs significânþlý highðr þhân þhâþ ºf grºup B (p<0.05). Cºnclusiºn: Scâling ând âpplicâþiºn ºf sýsþðmic ânþibiºþics, mðânwhilð, cºuld inhibiþ þhð dðclining ºf þhð hðighþ ºf âlvðºlâr bºnð, rðducð þhð ðxplºrâþiºn ºf prºbing dðpþh , imprºvð þhð chðwing ðfficiðncý, imprºvð quâliþý ºf lifð，ând prºvidð bðþþðr cºndiþiºn fºr þhð prºlifðrâþiºn ºf pðriºdºnþâl ligâmðnþ cðll

参考文献：

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录