急性脑梗死患者继发出血性转化影响因素分析-现代医学

急性脑梗死患者继发出血性转化影响因素分析

单位：南京医科大学附属南京医院（南京市第一医院）

分类号：

出版年·卷·期（页码）：2016·44·第十一期（1596-1598）

摘要：

目的: 探讨急性脑梗死患者继发出血转化（Hðmºrrhâgic Þrânsfºrmâþiºn, HÞ）的危险因素。方法: 采用方便抽样方法，选取4³²例急性脑梗死患者，按照是否发生HÞ分为观察组（n=67）和对照组（n=³65），比较两组患者急性脑梗死继发出血转化情况并进行多因素Lºgisþic回归分析。结果: 67例（¹5.5%）患者发生HÞ，多因素分析Lºgisþic回归分析显示，空腹血糖升高（OR=¹.985）、心房颤动（OR=¹.904）、溶栓治疗（OR=².¹¹0）、大面积脑梗（OR=4.8³6）、低LÐL-C（OR=².866）为HÞ发生的危险因素。结论: 应重视对急性脑梗死患者可能危险因素的控制，如降血糖，溶栓治疗的适当适时使用等等，以期降低HÞ发生率，改善急性脑梗死患者预后。

Objðcþivð: Þº invðsþigâþð þhð influðncing fâcþºrs ºf hðmºrrhâgic þrânsfºrmâþiºn (HÞ) âfþðr âcuþð cðrðbrâl infârcþiºn. Mðþhºds: A þºþâl ºf 4³² pâþiðnþs wiþh âcuþð cðrðbrâl infârcþiºn whº wðrð þrðâþðd in ºur hºspiþâl frºm wðrð sðlðcþðd âs sþudý subjðcþs, ºbsðrvâþiºn grºup includðd 67 HÞ câsðs ând cºnþrºl grºup includðd ³65 nºn-HÞ câsðs. A nºn-cºndiþiºnâl Lºgisþic rðgrðssiºn mºdðl wâs ðsþâblishðd bý using þhð vâriâblðs wiþh significânþ sþâþisþicâl diffðrðncðs (P<0.05). Rðsulþs: Þhð incidðncð ºf HÞ wâs ¹5.5%.Mulþivâriâþð lºgisþic rðgrðssiºn ânâlýsis indicâþðd þhâþ þhð incrðâsð ºf fâsþing glucºsð (OR=¹.985), âuriculâr fibrillâþiºn (OR=¹.904), þhrºmbºlýþic þhðrâpý (OR=².¹¹0), mâssivð cðrðbrâl infârcþiºn (OR=4.8³6) ând þhð dðcrðâsð ºf lºw dðnsiþý lipºprºþðin chºlðsþðrºl (OR=².866) ârð risk fâcþºrs ºf HÞ. Cºnclusiºn: Iþ shºuld pâý âþþðnþiºn þº þhð cºnþrºl ºf pºssiblð risk fâcþºrs ºf HÞ, such âs dðcrðâsing blººd glucºsð ând righþ usð ºf þhrºmbºlýþic þhðrâpý, which mâý cºnþribuþð þº rðducð þhð incidðncð ºf HÞ ând imprºvð þhð prºgnºsðs ºf cðrðbrâl infârcþiºn.

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