[ABSTRACT] Objective: To observe the effects of Oxcarbazepine suspension single drug on the treatment of partial seizure epilepsy in children and the influences on brain electrical activity. Methods: Eighty children with epilepsy seizures who were treated in our hospital from January 2010 to January 2011 were selected and randomly divided into the observation group and the control group, 40 cases in each group. The patients of the observation group were treated by Oxcarbazepine (OXC), while the patients of the control group were treated by carbamazepine (CBZ) . Then we observed and compared the clinical efficacy and EEG activity between two groups after treatment with different medicine. Results: In the observation group, the θ wave was (16.99 ± 5.62) after the treatment which was higher than before (13.12 ± 5.39). In the control group, the θ wave was (18.61 ± 6.29) after treatment which was higher than before (13.09 ± 5.21); the a wave was (6.89 ± 1.35) after treatment which was lower than before. The clinical effect and EEG of patients after treatment were compared between two groups, and there was no statistically significant difference (P > 0.05). Conclusion: OXC and CBZ have consistent effect on the treatment of children with a partial seizures at the age of 2-4 years old, but the OXC has less effect on EEG background activities. |