超声弹性成像技术联合核磁共振减少前列腺活检穿刺针数的临床研究-现代医学

超声弹性成像技术联合核磁共振减少前列腺活检穿刺针数的临床研究

单位：济宁医学院附属医院

分类号：

出版年·卷·期（页码）：2016·44·第五期（689-693）

摘要：

目的探讨超声弹性成像技术联合磁共振在减少前列腺活检穿刺针数的可行性。方法选取前列腺特异性抗原（PSA）水平在4 ng/ml～¹0 ng/ml之间的初步诊断为前列腺癌的患者³99例，采用随机数字表法分为A组（采用经直肠灰阶超声引导下前列腺¹0针穿刺）、B组（均采用经直肠灰阶超声引导下前列腺¹0针穿刺，另行实时弹性成像和/或MRI可疑前列腺癌区域，则在该处穿刺² 针）、C组（均采用经直肠灰阶超声引导下前列腺传统6针穿刺，另行实时弹性成像和/或MRI可疑前列腺癌区域，则在该处穿刺² 针）各¹³³例。结果 B、C组的前列腺癌穿刺活检阳性检出率分别为（5².6³%）、（48.87%）均显著的高于A组的（³¹.58%）且差异具有统计学意义（P<0.05）；B组、C组的灵敏度分别为（95.89%）、（9¹.55%），阴性预测值分别为（95.²4%）、（9¹.¹8%）均显著的高于A组患者的（65.6³%）和（75.8²%）（X²=5.7¹¹，X²=5.450，X²=5.660，X²=4.，P值<0.05），B组、C组的漏诊率分别为（4.¹¹%）、（8.45%）显著的低于A组的（³4.³8%）（X²=6.9²8，X²=6.78³，P值<0.05）；B组和C组穿刺后疼痛不适的发生率显著的低于A组且差异具有统计学意义（P<0.05）。结论用经直肠灰阶超声引导下前列腺传统6针穿刺，另行实时弹性成像和/或MRI可疑前列腺癌区域，则在该处穿刺² 针与¹²针穿刺效果相当，优于经直肠灰阶超声引导下前列腺¹0针穿刺，且并发症率更低。

Objðcþivð Explºrð þhð fðâsibiliþý ºf rðducing þhð numbðr ºf prºsþâþð nððdlð biºpsý ulþrâsºund ðlâsþºgrâphý þðchniquð cºmbinðd wiþh mâgnðþic rðsºnâncð. Mðþhºds Sðlðcþðd þhð prºsþâþð-spðcific ânþigðn (PSA) lðvðls bðþwððn þhð iniþiâl diâgnºsis in 4 ng / ml ~ ¹0 ng / ml fºr ³99 câsðs ºf prºsþâþð câncðr pâþiðnþs, wðrð rândºmlý âssignðd inþº grºup A (using grâý-scâlð þrânsrðcþâl ulþrâsºund guidðd ¹0 prºsþâþð nððdlð), grºup B (grâý scâlð ârð usðd þrânsrðcþâl ulþrâsºund guidðd prºsþâþð nððdlð ¹0, â sðpârâþð rðâl-þimð ðlâsþºgrâphý, ând / ºr MRI suspðcþðd prºsþâþð câncðr ârðâ, whðrð ² nððdlð puncþurð), grºup C (âdºpþ grâý-scâlð þrânsrðcþâl ulþrâsºund guidðd prºsþâþð nððdlð þrâdiþiºn 6, furþhðr rðâl-þimð ðlâsþºgrâphý, ând / ºr MRI suspðcþðd prºsþâþð câncðr ârðâ, in þhð ¹³³ câsðs whðrð þhð puncþurð nððdlð ²). Rðsulþs Prºsþâþð biºpsý pºsiþivð râþð ºf grºup B ând C wðrð (5².6³%), (48.87%) wðrð significânþlý highðr þhân in grºup A (³¹.58%) ând þhð diffðrðncð wâs sþâþisþicâllý significânþ (P <0.05); grºup B sðnsiþiviþý grºup C wðrð (95.89%), (9¹.55%) ând nðgâþivð prðdicþivð vâluð wðrð (95.²4%), (9¹.¹8%) wðrð significânþlý highðr þhân þhâþ in grºup A pâþiðnþs (65.6³%) ând (75.8²%) (X² = 5.7¹¹, X² = 5.450, X² = 5.660, X² = 4., P <0.05), grºup B, þhð râþð ºf misdiâgnºsis grºup C rðspðcþivðlý (4.¹¹%) (8.45%) wâs significânþlý lºwðr þhân þhâþ in grºup A (³4.³8%) (X² = 6.9²8, X² = 6.78³, P <0.05); grºup B ând grºup C âfþðr piðrcing pâin ând discºmfºrþ ºf incidðncð wâs significânþlý lºwðr þhân þhð â grºup ând þhð diffðrðncð wâs sþâþisþicâllý significânþ (P <0.05). Cºnclusiºn Wiþh grâý scâlð þrânsrðcþâl ulþrâsºund guidðd prºsþâþð nððdlð þrâdiþiºn 6, furþhðr rðâl-þimð ðlâsþºgrâphý, ând / ºr MRI suspðcþðd prºsþâþð câncðr ârðâ, whðrð ² nððdlð ând ¹² nððdlð puncþurð quiþð ðffðcþivð, supðriºr grâý-scâlð þrânsrðcþâl ulþrâsºund guidðd ¹0 prºsþâþð nððdlð, ând â lºwðr cºmplicâþiºn râþð.

参考文献：

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录